PDB entry 3h1p

View 3h1p on RCSB PDB site
Description: mature caspase-7 i213a with devd-cho inhibitor bound to active site
Deposited on 2009-04-13, released 2009-06-30
The last revision was dated 2021-10-13, with a file datestamp of 2021-10-08.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: caspase-7
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55210 (0-253)
      • conflict (121)
      • engineered mutation (163)
      • expression tag (254-259)
  • Chain 'B':
    Compound: caspase-7
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55210 (0-253)
      • conflict (121)
      • engineered mutation (163)
      • expression tag (254-259)
  • Chain 'C':
    Compound: n-acetyl-l-alpha-aspartyl-l-alpha-glutamyl-n-[(2s)-1-carboxy-3-hydroxypropan-2-yl]-l-valinamide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3H1P (Start-3)
  • Chain 'D':
    Compound: n-acetyl-l-alpha-aspartyl-l-alpha-glutamyl-n-[(2s)-1-carboxy-3-hydroxypropan-2-yl]-l-valinamide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3H1P (Start-3)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3h1pA (A:)
ttrdrvptyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvi
vyndcscakmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgd
rsktllekpklffiqacrgtelddgiqadsgpindtdanprykapveadflfaystvpgy
yswrspgrgswfvqalcsileehgkdleimqiltrvndrvarhfesqsddphfhekkqip
cvvsmltkelyfsqhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3h1pA (A:)
yqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsca
kmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrsktllek
pklffiqacrgtelddgiqykapveadflfaystvpgyyswrspgrgswfvqalcsilee
hgkdleimqiltrvndrvarhfesqsddphfhekkqipcvvsmltkelyfsq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3h1pB (B:)
ttrdrvptyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvi
vyndcscakmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgd
rsktllekpklffiqacrgtelddgiqadsgpindtdanprykapveadflfaystvpgy
yswrspgrgswfvqalcsileehgkdleimqiltrvndrvarhfesqsddphfhekkqip
cvvsmltkelyfsqhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3h1pB (B:)
tyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsc
akmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrsktlle
kpklffiqacrgtelddgiqykapveadflfaystvpgyyswrspgrgswfvqalcsile
ehgkdleimqiltrvndrvarhfesqsddphfhekkqipcvvsmltkelyfsqh

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >3h1pC (C:)
devx

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >3h1pD (D:)
devx