PDB entry 3h0s

View 3h0s on RCSB PDB site
Description: Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 7
Class: transferase
Keywords: TRANSFERASE, ACETYL-COA CARBOXYLASE, CARBOXYLTRANSFERASE, INHIBITOR, ACC, CT, ATP-binding, Biotin, Cytoplasm, Fatty acid biosynthesis, Ligase, Lipid synthesis, Metal-binding, Multifunctional enzyme, Nucleotide-binding
Deposited on 2009-04-10, released 2010-04-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2010-04-07, with a file datestamp of 2010-04-02.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: 0.166
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetyl-coa carboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: FAS3, ACC1, YNR016C, N3175
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3h0sa1, d3h0sa2
  • Chain 'B':
    Compound: acetyl-coa carboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: FAS3, ACC1, YNR016C, N3175
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3h0sb1, d3h0sb2
  • Chain 'C':
    Compound: acetyl-coa carboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: FAS3, ACC1, YNR016C, N3175
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3h0sc1, d3h0sc2
  • Heterogens: SO4, B38, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3h0sA (A:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepqgmvgikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3h0sA (A:)
lrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffis
neliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpq
edeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylylt
segmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagatsray
hdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnlqlgg
tqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptnde
tydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtv
enlipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrgfsgg
qrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvn
aragvlepqgmvgikfrreklldtmnrlddkyrelrerellpiygqislqfadlhdrssr
mvakgviskelewtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswypas
vdheddrqvatwieenyktlddklkglklesfa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3h0sB (B:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepqgmvgikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3h0sB (B:)
lrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffis
neliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpq
edeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylylt
segmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagatsray
hdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnlqlgg
tqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptnde
tydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtv
enlipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrgfsgg
qrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvn
aragvlepqgmvgikfrreklldtmnrlellpiygqislqfadlhdrssrmvakgviske
lewtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswypasvdheddrqva
twieenyktlddklkgl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3h0sC (C:)
masgsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkl
tddffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfk
igsfgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkg
fqylyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsglia
gatsrayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevyt
snlqlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvd
ftptndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvi
gvetrtvenlipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilan
wrgfsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqm
emyadvnaragvlepqgmvgikfrreklldtmnrlddkyrelrsqlsnkslapevhqqis
kqladrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlne
eylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglkle
sfaqdlakkirsdhdnaidglsevikmlstddkekllktlklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3h0sC (C:)
wlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffisneliedengelt
everepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpqedeffnkvteya
rkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylyltsegmetlkkfdk
ensvltertvingeerfviktiigsedglgveclrgsgliagatsrayhdiftitlvtcr
svgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnlqlggtqimynngvshl
tavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptndetydvrwmiegre
tesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtvenlipadpanpn
saetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrgfsggqrdmfnevlkyg
sfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvnaragvlepqgmv
gikfrreklldtmnrlellpiygqislqfadlhdrssrmvakgviskelewtearrfffw
rlrrrlneeylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktldd
klkglkle