PDB entry 3gym

View 3gym on RCSB PDB site
Description: Structure of Prostasin in Complex with Aprotinin
Class: hydrolase/inhibitor
Keywords: Prostasin, hCAP1, channel Activating, Aprotinin, inhibition, Disulfide bond, Pharmaceutical, Protease inhibitor, Secreted, Serine protease inhibitor, Cell membrane, Glycoprotein, Hydrolase, Membrane, Protease, Serine protease, Transmembrane, Zymogen, HYDROLASE/INHIBITOR COMPLEX
Deposited on 2009-04-03, released 2009-05-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-05-05, with a file datestamp of 2009-05-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.228
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostasin
    Species: Homo sapiens [TaxId:9606]
    Gene: hCAP1, PRSS8
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16651 (0-End)
      • engineered (109)
      • engineered (114)
      • engineered (158)
    Domains in SCOPe 2.06: d3gyma_
  • Chain 'B':
    Compound: Prostasin
    Species: Homo sapiens [TaxId:9606]
    Gene: hCAP1, PRSS8
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16651 (0-End)
      • engineered (109)
      • engineered (114)
      • engineered (158)
    Domains in SCOPe 2.06: d3gymb_
  • Chain 'I':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3gymi_
  • Chain 'J':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3gymj_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3gymA (A:)
itggssavagqwpwqvsityegvhvcggslvseqwvlsaahcfpsehhkeayevklgahq
ldsysedakvstlkdiiphpsylqegsqgdiallqlsrpitfsryirpislpaaqasfpn
glhctvtgwghvapsvslltpkplqqlevplisretcnslynidakpeephfvqedmvca
gyveggkdacqgdsggplscpveglwyltgivswgdacgarnrpgvytlassyaswiqsk
vtelqprvvpqtqesqpdsnl

    Sequence, based on observed residues (ATOM records): (download) 
    >3gymA (A:)
itggssavagqwpwqvsityegvhvcggslvseqwvlsaahcfpsehhkeayevklgahq
ldsysedakvstlkdiiphpsylqegsqgdiallqlsrpitfsryirpislpaaqasfpn
glhctvtgwghvapsvslltpkplqqlevplisretcnslynidakpeephfvqedmvca
gyveggkdacqgdsggplscpveglwyltgivswgdacgarnrpgvytlassyaswiqsk
v

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3gymB (B:)
itggssavagqwpwqvsityegvhvcggslvseqwvlsaahcfpsehhkeayevklgahq
ldsysedakvstlkdiiphpsylqegsqgdiallqlsrpitfsryirpislpaaqasfpn
glhctvtgwghvapsvslltpkplqqlevplisretcnslynidakpeephfvqedmvca
gyveggkdacqgdsggplscpveglwyltgivswgdacgarnrpgvytlassyaswiqsk
vtelqprvvpqtqesqpdsnl

    Sequence, based on observed residues (ATOM records): (download) 
    >3gymB (B:)
itggssavagqwpwqvsityegvhvcggslvseqwvlsaahcfpsehhkeayevklgahq
ldsysedakvstlkdiiphpsylqegsqgdiallqlsrpitfsryirpislpaaqasfpn
glhctvtgwghvapsvslltpkplqqlevplisretcnslynidakpeephfvqedmvca
gyveggkdacqgdsggplscpveglwyltgivswgdacgarnrpgvytlassyaswiqsk
v

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >3gymI (I:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

    Sequence, based on observed residues (ATOM records): (download) 
    >3gymI (I:)
pdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtc

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >3gymJ (J:)
rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga

    Sequence, based on observed residues (ATOM records): (download) 
    >3gymJ (J:)
pdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtc