PDB entry 3gxn

View 3gxn on RCSB PDB site
Description: Crystal structure of apo alpha-galactosidase A at pH 4.5
Class: hydrolase
Keywords: hydrolase, Disease mutation, Disulfide bond, Glycoprotein, Glycosidase, Lysosome, RNA editing
Deposited on 2009-04-02, released 2009-05-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.01 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-galactosidase A
    Species: Homo sapiens [TaxId:9606]
    Gene: GLA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3gxna1, d3gxna2
  • Chain 'B':
    Compound: Alpha-galactosidase A
    Species: Homo sapiens [TaxId:9606]
    Gene: GLA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3gxnb1, d3gxnb2
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3gxnA (A:)
ldnglartptmgwlhwerfmcnldcqeepdsciseklfmemaelmvsegwkdagyeylci
ddcwmapqrdsegrlqadpqrfphgirqlanyvhskglklgiyadvgnktcagfpgsfgy
ydidaqtfadwgvdllkfdgcycdslenladgykhmslalnrtgrsivyscewplymwpf
qkpnyteirqycnhwrnfadiddswksiksildwtsfnqerivdvagpggwndpdmlvig
nfglswnqqvtqmalwaimaaplfmsndlrhispqakallqdkdviainqdplgkqgyql
rqgdnfevwerplsglawavaminrqeiggprsytiavaslgkgvacnpacfitqllpvk
rklgfyewtsrlrshinptgtvllqlentmqmslkdll

    Sequence, based on observed residues (ATOM records): (download) 
    >3gxnA (A:)
ldnglartptmgwlhwerfmcnldcqeepdsciseklfmemaelmvsegwkdagyeylci
ddcwmapqrdsegrlqadpqrfphgirqlanyvhskglklgiyadvgnktcagfpgsfgy
ydidaqtfadwgvdllkfdgcycdslenladgykhmslalnrtgrsivyscewplymwpf
qkpnyteirqycnhwrnfadiddswksiksildwtsfnqerivdvagpggwndpdmlvig
nfglswnqqvtqmalwaimaaplfmsndlrhispqakallqdkdviainqdplgkqgyql
rqgdnfevwerplsglawavaminrqeiggprsytiavaslgkgvacnpacfitqllpvk
rklgfyewtsrlrshinptgtvllqlentm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3gxnB (B:)
ldnglartptmgwlhwerfmcnldcqeepdsciseklfmemaelmvsegwkdagyeylci
ddcwmapqrdsegrlqadpqrfphgirqlanyvhskglklgiyadvgnktcagfpgsfgy
ydidaqtfadwgvdllkfdgcycdslenladgykhmslalnrtgrsivyscewplymwpf
qkpnyteirqycnhwrnfadiddswksiksildwtsfnqerivdvagpggwndpdmlvig
nfglswnqqvtqmalwaimaaplfmsndlrhispqakallqdkdviainqdplgkqgyql
rqgdnfevwerplsglawavaminrqeiggprsytiavaslgkgvacnpacfitqllpvk
rklgfyewtsrlrshinptgtvllqlentmqmslkdll

    Sequence, based on observed residues (ATOM records): (download) 
    >3gxnB (B:)
ldnglartptmgwlhwerfmcnldcqeepdsciseklfmemaelmvsegwkdagyeylci
ddcwmapqrdsegrlqadpqrfphgirqlanyvhskglklgiyadvgnktcagfpgsfgy
ydidaqtfadwgvdllkfdgcycdslenladgykhmslalnrtgrsivyscewplymwpf
qkpnyteirqycnhwrnfadiddswksiksildwtsfnqerivdvagpggwndpdmlvig
nfglswnqqvtqmalwaimaaplfmsndlrhispqakallqdkdviainqdplgkqgyql
rqgdnfevwerplsglawavaminrqeiggprsytiavaslgkgvacnpacfitqllpvk
rklgfyewtsrlrshinptgtvllqlentm