SCOPe 2.07: Structural Classification of Proteins

PDB entry 3gxd

View 3gxd on RCSB PDB site
Description: Crystal structure of Apo acid-beta-glucosidase pH 4.5
Class: hydrolase
Keywords: hydrolase, Alternative initiation, Disease mutation, Disulfide bond, Gaucher disease, Glycoprotein, Glycosidase, Ichthyosis, Lipid metabolism, Lysosome, Membrane, Sphingolipid metabolism
Deposited on 2009-04-02, released 2009-05-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: glucosylceramidase
Species: Homo sapiens [TaxId:9606]
Gene: GBA, GC, GLUC
Database cross-references and differences (RAF-indexed):
- Uniprot P04062 (0-496)
  - variant (494)
Domains in SCOPe 2.07: d3gxda1, d3gxda2
Chain 'B':
Compound: glucosylceramidase
Species: Homo sapiens [TaxId:9606]
Gene: GBA, GC, GLUC
Database cross-references and differences (RAF-indexed):
- Uniprot P04062 (0-496)
  - variant (494)
Domains in SCOPe 2.07: d3gxdb1, d3gxdb2
Chain 'C':
Compound: glucosylceramidase
Species: Homo sapiens [TaxId:9606]
Gene: GBA, GC, GLUC
Database cross-references and differences (RAF-indexed):
- Uniprot P04062 (0-496)
  - variant (494)
Domains in SCOPe 2.07: d3gxdc1, d3gxdc2
Chain 'D':
Compound: glucosylceramidase
Species: Homo sapiens [TaxId:9606]
Gene: GBA, GC, GLUC
Database cross-references and differences (RAF-indexed):
- Uniprot P04062 (0-496)
  - variant (494)
Domains in SCOPe 2.07: d3gxdd1, d3gxdd2
Heterogens: PO4, NAG, HOH

PDB Chain Sequences:

Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)

>3gxdA (A:)
arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanh
tgtgllltlqpeqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniir
vpmascdfsirtytyadtpddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwt
sptwlktngavngkgslkgqpgdiyhqtwaryfvkfldayaehklqfwavtaenepsagl
lsgypfqclgftpehqrdfiardlgptlansthhnvrllmlddqrlllphwakvvltdpe
aakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgskfweqsvrlgswdrg
mqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykqpmfyhl
ghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfl
etispgysihtylwhrq

Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)

>3gxdB (B:)
arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanh
tgtgllltlqpeqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniir
vpmascdfsirtytyadtpddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwt
sptwlktngavngkgslkgqpgdiyhqtwaryfvkfldayaehklqfwavtaenepsagl
lsgypfqclgftpehqrdfiardlgptlansthhnvrllmlddqrlllphwakvvltdpe
aakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgskfweqsvrlgswdrg
mqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykqpmfyhl
ghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfl
etispgysihtylwhrq

Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)

>3gxdC (C:)
arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanh
tgtgllltlqpeqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniir
vpmascdfsirtytyadtpddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwt
sptwlktngavngkgslkgqpgdiyhqtwaryfvkfldayaehklqfwavtaenepsagl
lsgypfqclgftpehqrdfiardlgptlansthhnvrllmlddqrlllphwakvvltdpe
aakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgskfweqsvrlgswdrg
mqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykqpmfyhl
ghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfl
etispgysihtylwhrq

Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)

>3gxdD (D:)
arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanh
tgtgllltlqpeqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniir
vpmascdfsirtytyadtpddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwt
sptwlktngavngkgslkgqpgdiyhqtwaryfvkfldayaehklqfwavtaenepsagl
lsgypfqclgftpehqrdfiardlgptlansthhnvrllmlddqrlllphwakvvltdpe
aakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgskfweqsvrlgswdrg
mqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykqpmfyhl
ghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfl
etispgysihtylwhrq