PDB entry 3gxb

View 3gxb on RCSB PDB site
Description: Crystal structure of VWF A2 domain
Class: cell adhesion
Keywords: VWA-like fold, Blood coagulation, Cell adhesion, Cleavage on pair of basic residues, Disease mutation, Disulfide bond, Extracellular matrix, Glycoprotein, Hemostasis, Isopeptide bond, Secreted, von Willebrand disease
Deposited on 2009-04-02, released 2009-05-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: von willebrand factor
    Species: Homo sapiens [TaxId:9606]
    Gene: F8VWF, VWF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04275 (0-176)
      • expression tag (177)
    Domains in SCOPe 2.08: d3gxba1, d3gxba2
  • Chain 'B':
    Compound: von willebrand factor
    Species: Homo sapiens [TaxId:9606]
    Gene: F8VWF, VWF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04275 (0-176)
      • expression tag (177)
    Domains in SCOPe 2.08: d3gxbb1, d3gxbb2
  • Heterogens: NAG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3gxbA (A:)
    mvldvafvlegsdkigeadfnrskefmeeviqrmdvgqdsihvtvlqysymvtveypfse
    aqskgdilqrvreiryqggnrtntglalrylsdhsflvsqgdreqapnlvymvtgnpasd
    eikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvlqrccsphh
    hhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3gxbA (A:)
    mvldvafvlegsdkigeadfnrskefmeeviqrmdvgqdsihvtvlqysymvtveypfse
    aqskgdilqrvreiryqggnrtntglalrylsdhsflvsqgdreqapnlvymvtgnpasd
    eikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvlqrccsp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3gxbB (B:)
    mvldvafvlegsdkigeadfnrskefmeeviqrmdvgqdsihvtvlqysymvtveypfse
    aqskgdilqrvreiryqggnrtntglalrylsdhsflvsqgdreqapnlvymvtgnpasd
    eikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvlqrccsphh
    hhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3gxbB (B:)
    mvldvafvlegsdkigeadfnrskefmeeviqrmdvgqdsihvtvlqysymvtveypfse
    aqskgdilqrvreiryqggnrtntglalrylsdhsflvsqgdreqapnlvymvtgnpasd
    eikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvlqrccsp