PDB entry 3gww

View 3gww on RCSB PDB site
Description: Leucine transporter LeuT in complex with S-fluoxetine
Class: transport protein
Keywords: NEUROTRANSMITTER, TRANSMEMBRANE TRANSPORT, INTEGRAL MEMBRANE PROTEIN, ANTIDEPRESSANT, NSS, TRANSPORT PROTEIN, Symport, Transmembrane, Transport
Deposited on 2009-04-01, released 2009-05-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.46 Å
R-factor: 0.205
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transporter
    Species: Aquifex aeolicus [TaxId:224324]
    Gene: aq_2077, LeuT, snf
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3gwwa_
  • Heterogens: NA, LEU, SFX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3gwwA (A:)
mevkrehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmw
iewamgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfai
kflvglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinv
silirgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkd
pgvwiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisip
aavaffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaim
qpmiafledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffgltel
iiffwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeeth
wtvwitrfyiiglflfltflvflaerrrnhesagt

    Sequence, based on observed residues (ATOM records): (download) 
    >3gwwA (A:)
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpepppdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirgisk
gierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwiaavg
qifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaffgva
navaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiafled
elklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwifga
dkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwitrfy
iiglflfltflvflaerrrnh