PDB entry 3gws

View 3gws on RCSB PDB site
Description: Crystal Structure of T3-Bound Thyroid Hormone Receptor
Class: Hormone activator
Keywords: Thyroid hormone receptor, T3, hinge, Alternative splicing, Deafness, Disease mutation, DNA-binding, Metal-binding, Nucleus, Polymorphism, Receptor, Transcription, Transcription regulation, Zinc, Zinc-finger, Hormone activator
Deposited on 2009-04-01, released 2009-04-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-04-28, with a file datestamp of 2009-04-24.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.193
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'X':
    Compound: Thyroid hormone receptor beta
    Species: Homo sapiens [TaxId:9606]
    Gene: THRB, ERBA2, NR1A2, THR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3gwsx_
  • Heterogens: T3, HOH

PDB Chain Sequences:

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >3gwsX (X:)
eelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpedigqapivnapeg
gkvdleafshftkiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslraavry
dpesetltlngemavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllmss
drpglacveriekyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrflh
mkvecptelfpplflevfe

    Sequence, based on observed residues (ATOM records): (download) 
    >3gwsX (X:)
eelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpedigvdleafshft
kiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslraavrydpesetltlnge
mavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllmssdrpglacverie
kyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrflhmkvecptelfpp
lflevfe