PDB entry 3gvv

View 3gvv on RCSB PDB site
Description: Single-chain UROD Y164G (GY) mutation
Class: lyase
Keywords: uroporphyrinogen, decarboxylase, lyase, heme biosynthesis, Acetylation, Cytoplasm, Disease mutation, Phosphoprotein, Porphyrin biosynthesis
Deposited on 2009-03-31, released 2009-07-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uroporphyrinogen decarboxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: UROD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06132
      • engineered (216)
    Domains in SCOPe 2.08: d3gvva_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3gvvA (A:)
meanglgpqgfpelkndtflraawgeetdytpvwcmrqagrylpefretraaqdffstcr
speacceltlqplrrfpldaaiifsdilvvpqalgmevtmvpgkgpsfpeplreeqdler
lrdpevvaselgyvfqaitltrqrlagrvpligfagapwtlmtymvegggsstmaqakrw
lyqrpqashqllriltdalvpylvgqvvagaqalqlyeshaghlgpqlfnkfalpyirdv
akqvkarlreaglapvpmiifakdghfaleelaqagyevvgldwtvapkkarecvgktvt
lqgnldpcalyaseeeigqlvkqmlddfgphryianlghglypdmdpehvgafvdavhkh
srllrqn

    Sequence, based on observed residues (ATOM records): (download) 
    >3gvvA (A:)
fpelkndtflraawgeetdytpvwcmrqagrylpefretraaqdffstcrspeacceltl
qplrrfpldaaiifsdilvvpqalgmevtmvpgkgpsfpeplreeqdlerlrdpevvase
lgyvfqaitltrqrlagrvpligfagapwtlmtymvegggsstmaqakrwlyqrpqashq
llriltdalvpylvgqvvagaqalqlyeshaghlgpqlfnkfalpyirdvakqvkarlre
aglapvpmiifakdghfaleelaqagyevvgldwtvapkkarecvgktvtlqgnldpcal
yaseeeigqlvkqmlddfgphryianlghglypdmdpehvgafvdavhkhsrllrq