PDB entry 3gv5

View 3gv5 on RCSB PDB site
Description: Human DNA polymerase iota in complex with T template DNA and incoming ddADP
Class: transferase/DNA
Keywords: Y-family polymerase, polymerase iota, error prone replication, DNA damage, DNA repair, DNA replication, DNA synthesis, DNA-binding, DNA-directed DNA polymerase, Magnesium, Metal-binding, Mutator protein, Nucleotidyltransferase, Nucleus, Schiff base, Transferase, TRANSFERASE-DNA COMPLEX
Deposited on 2009-03-30, released 2009-06-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: DNA polymerase iota
    Species: Homo sapiens [TaxId:9606]
    Gene: POLI, RAD30B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3gv5b1, d3gv5b2
  • Chain 'D':
    Compound: DNA polymerase iota
    Species: Homo sapiens [TaxId:9606]
    Gene: POLI, RAD30B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3gv5d1, d3gv5d2
  • Chain 'E':
    Compound: 5'-d(*gp*tp*gp*gp*ap*tp*gp*ap*g)-3'
  • Chain 'F':
    Compound: 5'-d(p*cp*ap*tp*tp*cp*tp*cp*ap*tp*cp*cp*ap*c)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*tp*gp*gp*ap*tp*gp*ap*g)-3'
  • Chain 'T':
    Compound: 5'-d(p*cp*ap*tp*tp*cp*tp*cp*ap*tp*cp*cp*ap*c)-3'
  • Heterogens: CA, GOL, ADI, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3gv5B (B:)
meladvgaaassqgvhdqvlptpnassrvivhvdldcfyaqvemisnpelkdkplgvqqk
ylvvtcnyearklgvkklmnvrdakekcpqlvlvngedltryremsykvtelleefspvv
erlgfdenfvdltemvekrlqqlqsdelsavtvsghvynnqsinlldvlhirllvgsqia
aemreamynqlgltgcagvasnkllaklvsgvfkpnqqtvllpescqhlihslnhikeip
gigyktakclealginsvrdlqtfspkilekelgisvaqriqklsfgednspvilsgppq
sfseedsfkkcsseveaknkieellasllnrvcqdgrkphtvrliirryssekhygresr
qcpipshviqklgtgnydvmtpmvdilmklfrnmvnvkmpfhltllsvcfcnlkalntak

    Sequence, based on observed residues (ATOM records): (download) 
    >3gv5B (B:)
rvivhvdldcfyaqvemisnpelkdkplgvqqkylvvtcnyearklgvkklmnvrdakek
cpqlvlvngedltryremsykvtelleefspvverlgfdenfvdltemvekrlqqlqsde
lsavtvsghvynnqsinlldvlhirllvgsqiaaemreamynqlgltgcagvasnkllak
lvsgvfkpnqqtvllpescqhlihslnhikeipgigyktakclealginsvrdlqtfspk
ilekelgisvaqriqklsfgednspvilsgppqsfseedsfkkcsseveaknkieellas
llnrvcqdgrkphtvrliirrysgresrqcpipshviqklnydvmtpmvdilmklfrnmv
nvkmpfhltllsvcfcnlk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3gv5D (D:)
meladvgaaassqgvhdqvlptpnassrvivhvdldcfyaqvemisnpelkdkplgvqqk
ylvvtcnyearklgvkklmnvrdakekcpqlvlvngedltryremsykvtelleefspvv
erlgfdenfvdltemvekrlqqlqsdelsavtvsghvynnqsinlldvlhirllvgsqia
aemreamynqlgltgcagvasnkllaklvsgvfkpnqqtvllpescqhlihslnhikeip
gigyktakclealginsvrdlqtfspkilekelgisvaqriqklsfgednspvilsgppq
sfseedsfkkcsseveaknkieellasllnrvcqdgrkphtvrliirryssekhygresr
qcpipshviqklgtgnydvmtpmvdilmklfrnmvnvkmpfhltllsvcfcnlkalntak

    Sequence, based on observed residues (ATOM records): (download) 
    >3gv5D (D:)
ssrvivhvdldcfyaqvemisnpelkdkplgvqqkylvvtcnyearklgvkklmnvrdak
ekcpqlvlvngedltryremsykvtelleefspvverlgfdenfvdltemvekrlqqlqs
delsavtvsghvynnqsinlldvlhirllvgsqiaaemreamynqlgltgcagvasnkll
aklvsgvfkpnqqtvllpescqhlihslnhikeipgigyktakclealginsvrdlqtfs
pkilekelgisvaqriqklsfgednspvilsgppqsfseedsfkkcsseveaknkieell
asllnrvcqdgrkphtvrliirryssgresrqcpipshviqklnydvmtpmvdilmklfr
nmvnvkmpfhltllsvcfcnlka

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.