PDB entry 3gt9

View 3gt9 on RCSB PDB site
Description: Structure of an ML-IAP/XIAP chimera bound to a peptidomimetic
Class: apoptosis
Keywords: zinc binding, peptide complex, apoptosis inhibition, peptidomimetic, small molecule, drug design, apoptosis, metal-binding
Deposited on 2009-03-27, released 2010-03-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Baculoviral IAP repeat-containing 7
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6R308
      • engineered (110)
      • engineered (120-127)
    Domains in SCOPe 2.08: d3gt9a_
  • Chain 'B':
    Compound: Baculoviral IAP repeat-containing 7
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6R308
      • engineered (110)
      • engineered (120-128)
    Domains in SCOPe 2.08: d3gt9b_
  • Heterogens: ZN, 516, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3gt9A (A:)
mgsshhhhhhssgevprgshmleteeeeeegagatlsrgpafpgmgseelrlasfydwpl
taevppellaaagffhtghqdkvrcffcygglqswkrgddpwtehakwfpgcqfllrskg
qeyinnihlthsl

    Sequence, based on observed residues (ATOM records): (download) 
    >3gt9A (A:)
gpafpgmgseelrlasfydwpltaevppellaaagffhtghqdkvrcffcygglqswkrg
ddpwtehakwfpgcqfllrskgqeyinnih

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3gt9B (B:)
mgsshhhhhhssgevprgshmleteeeeeegagatlsrgpafpgmgseelrlasfydwpl
taevppellaaagffhtghqdkvrcffcygglqswkrgddpwtehakwfpgcqfllrskg
qeyinnihlthsl

    Sequence, based on observed residues (ATOM records): (download) 
    >3gt9B (B:)
gpafpgmgseelrlasfydwpltaevppellaaagffhtdkvrcffcygglqswkrgddp
wtehakwfpgcqfllrskgqeyinnihlt