PDB entry 3gph

View 3gph on RCSB PDB site
Description: human cytochrome p450 2e1 in complex with omega-imidazolyl-decanoic acid
Deposited on 2009-03-23, released 2010-05-12
The last revision was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2E1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP2E, CYP2E1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05181 (10-471)
      • expression tag (9)
  • Chain 'B':
    Compound: Cytochrome P450 2E1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP2E, CYP2E1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05181 (10-471)
      • expression tag (9)
  • Heterogens: HEM, OID, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3gphA (A:)
makktsskgklppgpfplpiignlfqlelknipksftrlaqrfgpvftlyvgsqrmvvmh
gykavkealldykdefsgrgdlpafhahrdrgiifnngptwkdirrfslttlrnygmgkq
gnesriqreahfllealrktqgqpfdptfligcapcnviadilfrkhfdyndekflrlmy
lfnenfhllstpwlqlynnfpsflhylpgshrkviknvaevkeyvservkehhqsldpnc
prdltdcllvemekekhsaerlytmdgitvtvadlffagtettsttlrygllilmkypei
eeklheeidrvigpsripaikdrqempymdavvheiqrfitlvpsnlpheatrdtifrgy
lipkgtvvvptldsvlydnqefpdpekfkpehflnengkfkysdyfkpfstgkrvcageg
larmelflllcailqhfnlkplvdpkdidlspihigfgcippryklcviprshhhh

    Sequence, based on observed residues (ATOM records):
    >3gphA (A:)
klppgpfplpiignlfqlelknipksftrlaqrfgpvftlyvgsqrmvvmhgykavkeal
ldykdefsgrgdlpafhahrdrgiifnngptwkdirrfslttlrnygkqgnesriqreah
fllealrktqgqpfdptfligcapcnviadilfrkhfdyndekflrlmylfnenfhllst
pwlqlynnfpsflhylpgshrkviknvaevkeyvservkehhqsldpncprdltdcllve
mekekhsaerlytmdgitvtvadlffagtettsttlrygllilmkypeieeklheeidrv
igpsripaikdrqempymdavvheiqrfitlvpsnlpheatrdtifrgylipkgtvvvpt
ldsvlydnqefpdpekfkpehflnengkfkysdyfkpfstgkrvcageglarmelflllc
ailqhfnlkplvdpkdidlspihigfgcippryklcviprs

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3gphB (B:)
makktsskgklppgpfplpiignlfqlelknipksftrlaqrfgpvftlyvgsqrmvvmh
gykavkealldykdefsgrgdlpafhahrdrgiifnngptwkdirrfslttlrnygmgkq
gnesriqreahfllealrktqgqpfdptfligcapcnviadilfrkhfdyndekflrlmy
lfnenfhllstpwlqlynnfpsflhylpgshrkviknvaevkeyvservkehhqsldpnc
prdltdcllvemekekhsaerlytmdgitvtvadlffagtettsttlrygllilmkypei
eeklheeidrvigpsripaikdrqempymdavvheiqrfitlvpsnlpheatrdtifrgy
lipkgtvvvptldsvlydnqefpdpekfkpehflnengkfkysdyfkpfstgkrvcageg
larmelflllcailqhfnlkplvdpkdidlspihigfgcippryklcviprshhhh

    Sequence, based on observed residues (ATOM records):
    >3gphB (B:)
klppgpfplpiignlfqlelknipksftrlaqrfgpvftlyvgsqrmvvmhgykavkeal
ldykdefsgrgdlpafhahrdrgiifnngptwkdirrfslttlrnygkqgnesriqreah
fllealrktqgqpfdptfligcapcnviadilfrkhfdyndekflrlmylfnenfhllst
pwlqlynnfpsflhylpgshrkviknvaevkeyvservkehhqsldpncprdltdcllve
mekekhsaerlytmdgitvtvadlffagtettsttlrygllilmkypeieeklheeidrv
igpsripaikdrqempymdavvheiqrfitlvpsnlpheatrdtifrgylipkgtvvvpt
ldsvlydnqefpdpekfkpehflnengkfkysdyfkpfstgkrvcageglarmelflllc
ailqhfnlkplvdpkdidlspihigfgcippryklcviprs