PDB entry 3gok

View 3gok on RCSB PDB site
Description: Binding site mapping of protein ligands
Deposited on 2009-03-19, released 2010-03-02
The last revision was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.239
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: MAP kinase-activated protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: 9261, MAPKAPK2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: P4O, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3gokA (A:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokA (A:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgaftereaseim
ksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettyvapevlgpeky
dkscdmwslgvimyillcgyppfysnspgmktrirmgqyefpnpewsevseevkmlirnl
lkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3gokB (B:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokB (B:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafterease
imksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevlg
pekydkscdmwslgvimyillcgyppfysnispgmktrirmgqyefpnpewsevseevkm
lirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3gokC (C:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokC (C:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgaftereaseim
ksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevlgpe
kydkscdmwslgvimyillcgyppfyspgmktrirmgqyefpnpewsevseevkmlirnl
lkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3gokD (D:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokD (D:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgaftereaseim
ksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettapevlgpekydk
scdmwslgvimyillcgyppfysnspgmktrirmgqyefpnpewsevseevkmlirnllk
teptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3gokE (E:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokE (E:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafterease
imksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevlg
pekydkscdmwslgvimyillcgyppfysnispgmktrirmgqyefpnpewsevseevkm
lirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'F':
    Sequence, based on SEQRES records:
    >3gokF (F:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokF (F:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgaftereaseim
ksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevlgpe
kydkscdmwslgvimyillcgyppfypgmktrirmgqyefpnpewsevseevkmlirnll
kteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'G':
    Sequence, based on SEQRES records:
    >3gokG (G:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokG (G:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgaftereaseim
ksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettyyvapevlgpek
ydkscdmwslgvimyillcgyppfysnspgmktrirmgqyefpnpewsevseevkmlirn
llkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'H':
    Sequence, based on SEQRES records:
    >3gokH (H:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokH (H:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafterease
imksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevlg
pekydkscdmwslgvimyillcgyppfysnispgmktrirmgqyefpnpewsevseevkm
lirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'I':
    Sequence, based on SEQRES records:
    >3gokI (I:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokI (I:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgaftereaseim
ksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevlgpe
kydkscdmwslgvimyillcgyppfypgmktrirmgqyefpnpewsevseevkmlirnll
kteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'J':
    Sequence, based on SEQRES records:
    >3gokJ (J:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokJ (J:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgaftereaseim
ksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettapevlgpekydk
scdmwslgvimyillcgyppfysnspgmktrirmgqyefpnpewsevseevkmlirnllk
teptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'K':
    Sequence, based on SEQRES records:
    >3gokK (K:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokK (K:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafterease
imksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevlg
pekydkscdmwslgvimyillcgyppfysnispgmktrirmgqyefpnpewsevseevkm
lirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe

  • Chain 'L':
    Sequence, based on SEQRES records:
    >3gokL (L:)
gamgsgamgsqqfpqfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekf
alkmlqdcpkarrevelhwrasqcphivrivdvyenlyagrkcllivmecldggelfsri
qdrgdqaftereaseimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgf
akettshnslttpcytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhgla
ispgmktrirmgqyefpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstk
vpqtplhtsrvlkedkerwedvkeemtsalatmr

    Sequence, based on observed residues (ATOM records):
    >3gokL (L:)
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgaftereaseim
ksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettpyyvapevlgpe
kydkscdmwslgvimyillcgyppfypgmktrirmgqyefpnpewsevseevkmlirnll
kteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwe