PDB entry 3goi

View 3goi on RCSB PDB site
Description: Human glucokinase in complex with a synthetic activator
Class: transferase
Keywords: glucokinase, diabetes, allosteric activator, ATP-binding, Glycolysis, Kinase, Nucleotide-binding, Transferase
Deposited on 2009-03-19, released 2009-04-28
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-05-19, with a file datestamp of 2009-05-15.
Experiment type: XRAY
Resolution: 2.52 Å
R-factor: 0.209
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GCK, hCG_1745191, tcag7.801
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3goia1, d3goia2
  • Heterogens: GLC, LOI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3goiA (A:)
taltlveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegse
vgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyiseci
sdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaik
rrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegr
mcvntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlv
denllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrra
cesvstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrl
tpsceitfieseegsgrgaalvsavackkacmlgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3goiA (A:)
tlveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegsevgd
flsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyisecisdf
ldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaikrrg
dfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegrmcv
ntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlvden
llfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrraces
vstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrltps
ceitfieseegsgrgaalvsavackkac