PDB entry 3gj7

View 3gj7 on RCSB PDB site
Description: Crystal structure of human RanGDP-Nup153ZnF12 complex
Class: transport protein
Keywords: G protein, GDP, Ran, Nup153, nuclear pore, Zinc Finger, Acetylation, Cytoplasm, GTP-binding, Host-virus interaction, Isopeptide bond, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Protein transport, Transport, Ubl conjugation, DNA-binding, Metal-binding, mRNA transport, Nuclear pore complex, Translocation, Zinc, Zinc-finger, TRANSPORT PROTEIN
Deposited on 2009-03-07, released 2009-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-08-04, with a file datestamp of 2009-07-31.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: 0.188
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP-binding nuclear protein ran
    Species: Homo sapiens [TaxId:9606]
    Gene: RAN, ARA24, OK/SW-cl.81
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62826
      • engineered (39)
    Domains in SCOPe 2.08: d3gj7a_
  • Chain 'B':
    Compound: Nuclear pore complex protein Nup153
    Species: Rattus norvegicus [TaxId:10116]
    Gene: NUP153
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3gj7b_
  • Chain 'C':
    Compound: GTP-binding nuclear protein ran
    Species: Homo sapiens [TaxId:9606]
    Gene: RAN, ARA24, OK/SW-cl.81
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62826
      • engineered (39)
    Domains in SCOPe 2.08: d3gj7c_
  • Chain 'D':
    Compound: Nuclear pore complex protein Nup153
    Species: Rattus norvegicus [TaxId:10116]
    Gene: NUP153
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3gj7d_
  • Heterogens: MG, GDP, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3gj7A (A:)
gphmasaaqgepqvqfklvlvgdggtgkttfvkrhltgesekkyvatlgvevhplvfhtn
rgpikfnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvceni
pivlcgnkvdikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnle
fvampalappevvmdpalaaqyehdlevaqttalpdedddl

    Sequence, based on observed residues (ATOM records): (download) 
    >3gj7A (A:)
pqvqfklvlvgdggtgkttfvkrhltgesekkyvatlgvevhplvfhtnrgpikfnvwdt
agqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdi
kdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappe
vvmdpalaaqyehdlevaqtt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3gj7B (B:)
gplgsagsswqcdtcllqnkvtdnkciacqaaklplketakqtgigtpsksdkpastsgt
gfgdkfkpaigtwdcdtclvqnkpeavkcvacetpkpg

    Sequence, based on observed residues (ATOM records): (download) 
    >3gj7B (B:)
gtwdcdtclvqnkpeavkcvacetpkp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3gj7C (C:)
gphmasaaqgepqvqfklvlvgdggtgkttfvkrhltgesekkyvatlgvevhplvfhtn
rgpikfnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvceni
pivlcgnkvdikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnle
fvampalappevvmdpalaaqyehdlevaqttalpdedddl

    Sequence, based on observed residues (ATOM records): (download) 
    >3gj7C (C:)
pqvqfklvlvgdggtgkttfvkrhltgesekkyvatlgvevhplvfhtnrgpikfnvwdt
agqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdi
kdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappe
vvmdpalaaqyehdlevaqtta

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3gj7D (D:)
gplgsagsswqcdtcllqnkvtdnkciacqaaklplketakqtgigtpsksdkpastsgt
gfgdkfkpaigtwdcdtclvqnkpeavkcvacetpkpg

    Sequence, based on observed residues (ATOM records): (download) 
    >3gj7D (D:)
gtwdcdtclvqnkpeavkcvacetpkp