PDB entry 3giz

View 3giz on RCSB PDB site
Description: Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab
Class: immune system
Keywords: CD20, 2F2, Ofatumumab, Hu-MaxCD20, Fab, antibody, fully human antibody, IMMUNE SYSTEM
Deposited on 2009-03-07, released 2009-05-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-06-23, with a file datestamp of 2009-06-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.198
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3GIZ (0-221)
  • Chain 'L':
    Compound: Fab fragment of anti-CD20 antibody Ofatumumab, light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3GIZ (0-210)
    Domains in SCOPe 2.06: d3gizl1, d3gizl2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3gizL (L:)
    eivltqspatlslspgeratlscrasqsvssylawyqqkpgqaprlliydasnratgipa
    rfsgsgsgtdftltisslepedfavyycqqrsnwpitfgqgtrleikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnr