PDB entry 3ghw

View 3ghw on RCSB PDB site
Description: Human dihydrofolate reductase inhibitor complex
Class: oxidoreductase
Keywords: human dihydrofoalte reductase inhibitor complex, NADP, One-carbon metabolism, Oxidoreductase
Deposited on 2009-03-04, released 2009-09-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-09-22, with a file datestamp of 2009-09-18.
Experiment type: XRAY
Resolution: 1.24 Å
R-factor: 0.181
AEROSPACI score: 0.77 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: dihydrofolate reductase
  Species: Homo sapiens [TaxId:9606]
  Gene: DHFR, DHFRP1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00374 (0-185)
  Domains in SCOPe 2.08: d3ghwa_
• Heterogens: GHW, NDP, SO4, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3ghwA (A:)
  vgslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsi
  peknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssv
  ykeamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfe
  vyeknd