PDB entry 3ghs
View 3ghs on RCSB PDB site
Description: Human aldose reductase in complex with NADP+ and the inhibitor IDD594. Investigation of global effects of radiation damage on protein structure. Second stage of radiation damage.
Class: oxidoreductase
Keywords: OXIDOREDUCTASE, Acetylation, Cataract, Cytoplasm, NADP, Phosphoprotein, Polymorphism
Deposited on
2009-03-04, released
2009-03-24
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-06-30, with a file datestamp of
2009-06-26.
Experiment type: XRAY
Resolution: 1 Å
R-factor: 0.088
AEROSPACI score: 1.08
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: aldose reductase
Species: Homo sapiens [TaxId:9606]
Gene: AKR1B1, ALDR1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3ghsa_ - Heterogens: NDP, LDT, CIT, HOH