PDB entry 3ggc

View 3ggc on RCSB PDB site
Description: Human hypoxanthine-guanine phosphoribosyltransferase in complex with 9-(2-phosphonoethoxyethyl)hypoxanthine
Class: transferase
Keywords: purine salvage, phosphoribosyltransferase, acyclic nucleoside phosphonate, Disease mutation, Glycosyltransferase, Gout, Magnesium, Metal-binding, Transferase
Deposited on 2009-02-27, released 2009-08-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.78 Å
R-factor: 0.231
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: HPRT, HPRT1, HPT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ggca_
  • Chain 'B':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: HPRT, HPRT1, HPT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ggcb_
  • Heterogens: H26, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ggcA (A:)
atrspgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghh
ivalcvlkggykffadlldyikalnrnsdrsipmtvdfirlksycndqstgdikviggdd
lstltgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgf
eipdkfvvgyaldyneyfrdlnhvcvisetgkakyka

    Sequence, based on observed residues (ATOM records): (download) 
    >3ggcA (A:)
spgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiva
lcvlkggykffadlldyikalnrnsdrsipmtvdfirlksycqstgdikviggddlstlt
gknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeipdk
fvvgyaldyneyfrdlnhvcvisetgkakyka

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ggcB (B:)
atrspgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghh
ivalcvlkggykffadlldyikalnrnsdrsipmtvdfirlksycndqstgdikviggdd
lstltgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgf
eipdkfvvgyaldyneyfrdlnhvcvisetgkakyka

    Sequence, based on observed residues (ATOM records): (download) 
    >3ggcB (B:)
rspgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghiva
lcvlkggykffadlldyikalnrnsdrsipmtvdfirlksycndqstgdikvigddlstl
tgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeipd
kfvvgyaldyneyfrdlnhvcvisetgkakyka