PDB entry 3gfd

View 3gfd on RCSB PDB site
Description: Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN and mono-iodotyrosine (MIT)
Deposited on 2009-02-26, released 2009-05-12
The last revision was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: 0.145
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Iodotyrosine dehalogenase 1
    Species: Mus musculus [TaxId:10090]
    Gene: Dehal1, Iyd
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9DCX8 (Start-252)
      • expression tag (253-254)
  • Chain 'B':
    Compound: Iodotyrosine dehalogenase 1
    Species: Mus musculus [TaxId:10090]
    Gene: Dehal1, Iyd
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9DCX8 (Start-252)
      • expression tag (253)
  • Heterogens: FMN, IYR, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3gfdA (A:)
    maqvqpwvdedlkdstedlqveedaeewqeaeesvehipfshtrypeqemrmrsqefyel
    lnkrrsvrfissehvpmevienvikaagtapsgahtepwtfvvvkdpdmkhkireiieee
    eeinymkrmgkrwvtdlkklrtnwikeyldtapvlilifkqvhgfaangkkkvhyyneis
    vsiacglllaalqnaglvtvtttplncgprlrvllgrpshekllvllpvgypsrdatvpd
    lkrkaldqimvtvhhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >3gfdA (A:)
    svehipfshtrypeqemrmrsqefyellnkrrsvrfissehvpmevienvikaagtapsg
    ahtepwtfvvvkdpdmkhkireiieeeeeinymkrmgkrwvtdlkklrtnwikeyldtap
    vlilifkqvhgfngkkkvhyyneisvsiacglllaalqnaglvtvtttplncgprlrvll
    grpshekllvllpvgypsrdatvpdlkrkaldqimvtvhh
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3gfdB (B:)
    maqvqpwvdedlkdstedlqveedaeewqeaeesvehipfshtrypeqemrmrsqefyel
    lnkrrsvrfissehvpmevienvikaagtapsgahtepwtfvvvkdpdmkhkireiieee
    eeinymkrmgkrwvtdlkklrtnwikeyldtapvlilifkqvhgfaangkkkvhyyneis
    vsiacglllaalqnaglvtvtttplncgprlrvllgrpshekllvllpvgypsrdatvpd
    lkrkaldqimvtvhhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >3gfdB (B:)
    svehipfshtrypeqemrmrsqefyellnkrrsvrfissehvpmevienvikaagtapsg
    ahtepwtfvvvkdpdmkhkireiieeeeeinymkrmgkrwvtdlkklrtnwikeyldtap
    vlilifkqvhgfngkkkvhyyneisvsiacglllaalqnaglvtvtttplncgprlrvll
    grpshekllvllpvgypsrdatvpdlkrkaldqimvtvh