PDB entry 3gdh

View 3gdh on RCSB PDB site
Description: methyltransferase domain of human trimethylguanosine synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine (active form)
Deposited on 2009-02-24, released 2009-06-23
The last revision was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Trimethylguanosine synthase homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: TGS1, HCA137, NCOA6IP, PIMT
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Trimethylguanosine synthase homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: TGS1, HCA137, NCOA6IP, PIMT
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Trimethylguanosine synthase homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: TGS1, HCA137, NCOA6IP, PIMT
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MGP, SAH, PGR, PGO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3gdhA (A:)
gplgsevkkkknkkknkkvnglppeiaavpelakywaqryrlfsrfddgikldregwfsv
tpekiaehiagrvsqsfkcdvvvdafcgvggntiqfaltgmrviaididpvkialarnna
evygiadkieficgdflllasflkadvvflsppwggpdyataetfdirtmmspdgfeifr
lskkitnnivyflprnadidqvaslagpggqveieqnflnnklktitayfgdlirrpase
t

    Sequence, based on observed residues (ATOM records):
    >3gdhA (A:)
lppeiaavpelakywaqryrlfsrfddgikldregwfsvtpekiaehiagrvsqsfkcdv
vvdafcgvggntiqfaltgmrviaididpvkialarnnaevygiadkieficgdflllas
flkadvvflsppwggpdyataetfdirtmmspdgfeifrlskkitnnivyflprnadidq
vaslagpggqveieqnflnnklktitayfgd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3gdhB (B:)
gplgsevkkkknkkknkkvnglppeiaavpelakywaqryrlfsrfddgikldregwfsv
tpekiaehiagrvsqsfkcdvvvdafcgvggntiqfaltgmrviaididpvkialarnna
evygiadkieficgdflllasflkadvvflsppwggpdyataetfdirtmmspdgfeifr
lskkitnnivyflprnadidqvaslagpggqveieqnflnnklktitayfgdlirrpase
t

    Sequence, based on observed residues (ATOM records):
    >3gdhB (B:)
eiaavpelakywaqryrlfsrfddgikldregwfsvtpekiaehiagrvsqscdvvvdaf
cgvggntiqfaltgmrviaididpvkialarnnaevygiadkieficgdflllasflkad
vvflsppwggpdyataetfdirtmmspdgfeifrlskkitnnivyflprnadidqvasla
gpggqveieqnflnnklktitayfgdlir

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3gdhC (C:)
gplgsevkkkknkkknkkvnglppeiaavpelakywaqryrlfsrfddgikldregwfsv
tpekiaehiagrvsqsfkcdvvvdafcgvggntiqfaltgmrviaididpvkialarnna
evygiadkieficgdflllasflkadvvflsppwggpdyataetfdirtmmspdgfeifr
lskkitnnivyflprnadidqvaslagpggqveieqnflnnklktitayfgdlirrpase
t

    Sequence, based on observed residues (ATOM records):
    >3gdhC (C:)
vpelakywaqryrlfsrfddgikldregwfsvtpekiaehiagrvsqsfkcdvvvdafcg
vggntiqfaltgmrviaididpvkialarnnaevygiadkieficgdflllasflkadvv
flsppwggpdyataetfdirtmmspdgfeifrlskkitnnivyflprnadidqvaslagp
ggqveieqnflnnklktitayfgdlir