PDB entry 3gb6

View 3gb6 on RCSB PDB site
Description: Structure of Giardia fructose-1,6-biphosphate aldolase D83A mutant in complex with fructose-1,6-bisphosphate
Class: lyase
Keywords: Class II fructose-1,6-bisphosphate aldolase, glycolytic pathway, Giardia lamblia, drug target, Glycolysis, Lyase
Deposited on 2009-02-18, released 2009-03-31
The last revision prior to the SCOPe 2.03 freeze date was dated 2010-06-09, with a file datestamp of 2010-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.198
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fructose-bisphosphate aldolase
    Species: Giardia intestinalis [TaxId:5741]
    Gene: ald, FBPA
    Database cross-references and differences (RAF-indexed):
    • Uniprot O97447 (Start-322)
      • engineered (82)
      • see remark 999 (128)
    Domains in SCOPe 2.03: d3gb6a_
  • Chain 'B':
    Compound: Fructose-bisphosphate aldolase
    Species: Giardia intestinalis [TaxId:5741]
    Gene: ald, FBPA
    Database cross-references and differences (RAF-indexed):
    • Uniprot O97447 (Start-322)
      • engineered (82)
      • see remark 999 (128)
    Domains in SCOPe 2.03: d3gb6b_
  • Heterogens: ZN, P6F, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3gb6A (A:)
mplctlrqmlgearkhkygvgafnvnnmeqiqgimkavvqlkspvilqcsrgalkysdmi
ylkklceaalekhpdipicihlahgdtlesvkmaidlgfssvmidashhpfdenvritke
vvayahargvsveaelgtlggieedvqntvqltepqdakkfveltgvdalavaigtshga
ykfksesdirlaidrvktisdltgiplvmhgsssvpkdvkdminkyggkmpdavgvpies
ivhaigegvckinvdsdsrmamtgairkvfvehpekfdprdylgpgrdaitemlipkika
fgsaghagdykvvsleeakawyk

    Sequence, based on observed residues (ATOM records): (download) 
    >3gb6A (A:)
plctlrqmlgearkhkygvgafnvnnmeqiqgimkavvqlkspvilqcsrgalkysdmiy
lkklceaalekhpdipicihlahgdtlesvkmaidlgfssvmidashhpfdenvritkev
vayahargvsveaelgtlggientvqltepqdakkfveltgvdalavaigtshgaykfks
esdirlaidrvktisdltgiplvmhgsssvpkdvkdminkyggkmpdavgvpiesivhai
gegvckinvdsdsrmamtgairkvfvehpekfdprdylgpgrdaitemlipkikafgsag
hagdykvvsleeakawyk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3gb6B (B:)
mplctlrqmlgearkhkygvgafnvnnmeqiqgimkavvqlkspvilqcsrgalkysdmi
ylkklceaalekhpdipicihlahgdtlesvkmaidlgfssvmidashhpfdenvritke
vvayahargvsveaelgtlggieedvqntvqltepqdakkfveltgvdalavaigtshga
ykfksesdirlaidrvktisdltgiplvmhgsssvpkdvkdminkyggkmpdavgvpies
ivhaigegvckinvdsdsrmamtgairkvfvehpekfdprdylgpgrdaitemlipkika
fgsaghagdykvvsleeakawyk

    Sequence, based on observed residues (ATOM records): (download) 
    >3gb6B (B:)
plctlrqmlgearkhkygvgafnvnnmeqiqgimkavvqlkspvilqcsrgalkysdmiy
lkklceaalekhpdipicihlahgdtlesvkmaidlgfssvmidashhpfdenvritkev
vayahargvsveaelgtlggietvqltepqdakkfveltgvdalavaigtshgaykfkse
sdirlaidrvktisdltgiplvmhgsssvpkdvkdminkyggkmpdavgvpiesivhaig
egvckinvdsdsrmamtgairkvfvehpekfdprdylgpgrdaitemlipkikafgsagh
agdykvvsleeakawyk