PDB entry 3g93

View 3g93 on RCSB PDB site
Description: single ligand occupancy crystal structure of cytochrome p450 2b4 in complex with the inhibitor 1-biphenyl-4-methyl-1h-imidazole
Deposited on 2009-02-12, released 2009-05-12
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.239
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (0-471)
      • engineered mutation (1-7)
      • engineered mutation (9)
      • see remark 999 (201)
      • engineered mutation (206)
      • expression tag (472-475)
  • Chain 'B':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (0-471)
      • engineered mutation (1-7)
      • engineered mutation (9)
      • see remark 999 (201)
      • engineered mutation (206)
      • expression tag (472-475)
  • Chain 'C':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (0-471)
      • engineered mutation (1-7)
      • engineered mutation (9)
      • see remark 999 (201)
      • engineered mutation (206)
      • expression tag (472-475)
  • Chain 'D':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (0-471)
      • engineered mutation (1-7)
      • engineered mutation (9)
      • see remark 999 (201)
      • engineered mutation (206)
      • expression tag (472-475)
  • Heterogens: HEM, PB2, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3g93A (A:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhh

    Sequence, based on observed residues (ATOM records):
    >3g93A (A:)
kgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdaire
alvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeri
qeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsf
slissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfid
vyllrmekhhqnliltvlslffagtettsttlrygfllmlkyphvtervqkeieqvigsh
rppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipkntevfpvlssa
lhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelflffttilq
nfsiaspvppedidltpregnvppsyqirflarh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3g93B (B:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhh

    Sequence, based on observed residues (ATOM records):
    >3g93B (B:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrrsveeriqeearcl
veelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfslissfs
sqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidvyllrme
khqnliltvlslffagtettsttlrygfllmlkyphvtervqkeieqvigshrppalddr
akmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipkntevfpvlssalhdpryfe
tpntfnpghfldangalkrnegfmpfslgkriclgegiartelflffttilqnfsiaspv
ppedidltnvppsyqirflarh

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3g93C (C:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhh

    Sequence, based on observed residues (ATOM records):
    >3g93C (C:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrrsveeriqeearcl
veelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfslissfs
sqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidvyllrme
fhhqnliltvlslffagtettsttlrygfllmlkyphvtervqkeieqvigshrppaldd
rakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipkntevfpvlssalhdpryf
etpntfnpghfldangalkrnegfmpfslgkriclgegiartelflffttilqnfsiasp
vppedidltpvppsyqirflar

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3g93D (D:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhh

    Sequence, based on observed residues (ATOM records):
    >3g93D (D:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmsveeriqeearclve
elrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfslissfssq
vfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidvyllrmekd
hqnliltvlslffagtettsttlrygfllmlkyphvtervqkeieqvigshrppalddra
kmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipkntevfpvlssalhdpryfet
pntfnpghfldangalkrnegfmpfslgkriclgegiartelflffttilqnfsiaspvp
pedidltpvppsyqirflar