PDB entry 3g6d

View 3g6d on RCSB PDB site
Description: Crystal structure of the complex between CNTO607 Fab and IL-13
Class: immune system
Keywords: IL-13, antibody, complex, epitope, Cytokine, Glycoprotein, Secreted, MONOCLONAL ANTIBODY, IMMUNE SYSTEM
Deposited on 2009-02-06, released 2009-04-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-05-30, with a file datestamp of 2012-05-25.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.213
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-13
    Species: Homo sapiens [TaxId:9606]
    Gene: IL13, NC30
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3g6da_
  • Chain 'H':
    Compound: CNTO607 Fab Heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3G6D (0-End)
    Domains in SCOPe 2.07: d3g6dh1, d3g6dh2
  • Chain 'L':
    Compound: CNTO607 Fab Light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3G6D (0-End)
    Domains in SCOPe 2.07: d3g6dl1, d3g6dl2
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3g6dA (A:)
mgpvppstalrelieelvnitqnqkaplcngsmvwsinltagmycaaleslinvsgcsai
ektqrmlsgfcphkvsagqfsslhvrdtkievaqfvkdlllhlkklfregrfn

    Sequence, based on observed residues (ATOM records): (download) 
    >3g6dA (A:)
vppstalrelieelvnitqnqkaplcngsmvwsinltagmycaaleslinvsgcsaiekt
qrmlsgfcphkvsagqfsslhvrdtkievaqfvkdlllhlkklfre

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3g6dH (H:)
qvqlvesggglvqpggslrlscaasgftfnsywinwvrqapgkglewvsgiaydssntly
adsvkgrftisrdnskntlylqmnslraedtavyycarglgafhwdmqpdywgqgtlvtv
ssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >3g6dH (H:)
qvqlvesggglvqpggslrlscaasgftfnsywinwvrqapgkglewvsgiaydssntly
adsvkgrftisrdnskntlylqmnslraedtavyycarglgafhwdmqpdywgqgtlvtv
ssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3g6dL (L:)
syeltqppsvsvapgqtariscsgdniggtfvswyqqkpgqapvlviyddndrpsgiper
fsgsnsgntatltisgtqaedeadyycgtwdmvtnnvfgggtkltvlgqpkaapsvtlfp
psseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyls
ltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >3g6dL (L:)
syeltqppsvsvapgqtariscsgdniggtfvswyqqkpgqapvlviyddndrpsgiper
fsgsnsgntatltisgtqaedeadyycgtwdmvtnnvfgggtkltvlgqpkaapsvtlfp
psseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyls
ltpeqwkshrsyscqvthegstvektvapt