PDB entry 3g60

View 3g60 on RCSB PDB site
Description: Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Class: membrane protein
Keywords: P-glycoprotein, Pgp, multidrug resistance, membrane protein, cyclic peptide
Deposited on 2009-02-05, released 2009-03-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-11-13, with a file datestamp of 2013-11-08.
Experiment type: XRAY
Resolution: 4.4 Å
R-factor: 0.314
AEROSPACI score: -0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Multidrug resistance protein 1a
    Species: Mus musculus [TaxId:10090]
    Gene: Abcb1a, mCG_1178
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3g60a1, d3g60a2, d3g60a3, d3g60a4
  • Chain 'B':
    Compound: Multidrug resistance protein 1a
    Species: Mus musculus [TaxId:10090]
    Gene: Abcb1a, mCG_1178
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 0JZ

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3g60A (A:)
meleedlkgradknfskmgkkskkekkekkpavsvltmfryagwldrlymlvgtlaaiih
gvalplmmlifgdmtdsfasvgnvsknstnmseadkramfakleeemttyayyytgigag
vlivayiqvsfwclaagrqihkirqkffhaimnqeigwfdvhdvgelntrltddvskine
gigdkigmffqamatffggfiigftrgwkltlvilaispvlglsagiwakilssftdkel
hayakagavaeevlaairtviafggqkkelerynnnleeakrlgikkaitanismgaafl
liyasyalafwygtslviskeysigqvltvffsvligafsvgqaspnieafanargaaye
vfkiidnkpsidsfsksghkpdniqgnlefknihfsypsrkevqilkglnlkvksgqtva
lvgnsgcgksttvqlmqrlydpldgmvsidgqdirtinvrylreiigvvsqepvlfatti
aenirygredvtmdeiekavkeanaydfimklphqfdtlvgergaqlsggqkqriaiara
lvrnpkillldeatsaldteseavvqaaldkaregrttiviahrlstvrnadviagfdgg
viveqgnhdelmrekgiyfklvmtqtagneielgneackskdeidnldmsskdsgsslir
rrstrksicgphdqdrklstkealdedvppasfwrilklnstewpyfvvgifcaiinggl
qpafsvifskvvgvftnggppetqrqnsnlfsllflilgiisfitfflqgftfgkageil
tkrlrymvfksmlrqdvswfddpknttgalttrlandaaqvkgatgsrlavifqnianlg
tgiiisliygwqltllllaivpiiaiagvvemkmlsgqalkdkkelegsgkiateaienf
rtvvsltreqkfetmyaqslqipyrnamkkahvfgitfsftqammyfsyaacfrfgaylv
tqqlmtfenvllvfsaivfgamavgqvssfapdyakatvsashiiriiektpeidsystq
glkpnmlegnvqfsgvvfnyptrpsipvlqglslevkkgqtlalvgssgcgkstvvqlle
rfydpmagsvfldgkeikqlnvqwlraqlgivsqepilfdcsiaeniaygdnsrvvsyee
ivraakeanihqfidslpdkyntrvgdkgtqlsggqkqriaiaralvrqphillldeats
aldtesekvvqealdkaregrtciviahrlstiqnadlivviqngkvkehgthqqllaqk
giyfsmvsvqagakrsyvhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3g60A (A:)
vsvltmfryagwldrlymlvgtlaaiihgvalplmmlifgdmtdsfasvgnvsknstnms
eadkramfakleeemttyayyytgigagvlivayiqvsfwclaagrqihkirqkffhaim
nqeigwfdvhdvgelntrltddvskinegigdkigmffqamatffggfiigftrgwkltl
vilaispvlglsagiwakilssftdkelhayakagavaeevlaairtviafggqkkeler
ynnnleeakrlgikkaitanismgaaflliyasyalafwygtslviskeysigqvltvff
svligafsvgqaspnieafanargaayevfkiidnkpsidsfsksghkpdniqgnlefkn
ihfsypsrkevqilkglnlkvksgqtvalvgnsgcgksttvqlmqrlydpldgmvsidgq
dirtinvrylreiigvvsqepvlfattiaenirygredvtmdeiekavkeanaydfimkl
phqfdtlvgergaqlsggqkqriaiaralvrnpkillldeatsaldteseavvqaaldka
regrttiviahrlstvrnadviagfdggviveqgnhdelmrekgiyfklvmtqtldedvp
pasfwrilklnstewpyfvvgifcaiingglqpafsvifskvvgvftnggppetqrqnsn
lfsllflilgiisfitfflqgftfgkageiltkrlrymvfksmlrqdvswfddpknttga
lttrlandaaqvkgatgsrlavifqnianlgtgiiisliygwqltllllaivpiiaiagv
vemkmlsgqalkdkkelegsgkiateaienfrtvvsltreqkfetmyaqslqipyrnamk
kahvfgitfsftqammyfsyaacfrfgaylvtqqlmtfenvllvfsaivfgamavgqvss
fapdyakatvsashiiriiektpeidsystqglkpnmlegnvqfsgvvfnyptrpsipvl
qglslevkkgqtlalvgssgcgkstvvqllerfydpmagsvfldgkeikqlnvqwlraql
givsqepilfdcsiaeniaygdnsrvvsyeeivraakeanihqfidslpdkyntrvgdkg
tqlsggqkqriaiaralvrqphillldeatsaldtesekvvqealdkaregrtciviahr
lstiqnadlivviqngkvkehgthqqllaqkgiyfsmvsvqa

  • Chain 'B':
    No sequence available.