PDB entry 3g5v

View 3g5v on RCSB PDB site
Description: Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR
Deposited on 2009-02-05, released 2010-02-09
The last revision was dated 2011-10-12, with a file datestamp of 2011-10-07.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.229
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 806 light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3G5V (0-211)
  • Chain 'B':
    Compound: 808 heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3G5V (0-212)
  • Chain 'C':
    Compound: Epidermal Growth Factor Receptor peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3G5V (0-15)
  • Heterogens: ACT, GOL, FMT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >3g5vA (A:)
dilmtqspssmsvslgdtvsitchssqdinsnigwlqqkpgksfkgliyhgtnlddevps
rfsgsgsgadysltisslesedfadyycvqyaqfpwtfgggtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3g5vB (B:)
dvqlqesgpslvkpsqslsltctvtgysitsdfawnwirqfpgnklewmgyisysgntry
npslksrisitrdtssnqfflqlnsvtiedtatyycvtagrgfpywgqgtlvtvsaaktt
ppsvyplapgcgdttgssvtlgclvkgyfpesvtvtansgslsssvhtfpallqsdlytm
sssvtvpsstwpsetvtcsvahpassttvdkka

    Sequence, based on observed residues (ATOM records):
    >3g5vB (B:)
dvqlqesgpslvkpsqslsltctvtgysitsdfawnwirqfpgnklewmgyisysgntry
npslksrisitrdtssnqfflqlnsvtiedtatyycvtagrgfpywgqgtlvtvsaaktt
ppsvyplaptlgclvkgyfpesvtvtansgslsvhtfpallqsdlytmsssvtvpsstws
etvtcsvahpassttvdkka

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >3g5vC (C:)
cgadsyemeedgvrkc