PDB entry 3g5m

View 3g5m on RCSB PDB site
Description: Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory activity
Class: oxidoreductase
Keywords: Casimiroin, QR2, NQ02, Cytoplasm, FAD, Flavoprotein, Metal-binding, Oxidoreductase, Phosphoprotein, Polymorphism, Zinc
Deposited on 2009-02-05, released 2009-03-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-04-14, with a file datestamp of 2009-04-10.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: 0.185
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribosyldihydronicotinamide dehydrogenase [quinone]
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO2, NMOR2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3g5ma_
  • Chain 'B':
    Compound: Ribosyldihydronicotinamide dehydrogenase [quinone]
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO2, NMOR2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3g5mb_
  • Heterogens: ZN, XM5, FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3g5mA (A:)
magkkvlivyahqepksfngslknvavdelsrqgctvtvsdlyamnfepratdkditgtl
snpevfnygvetheaykqrslasditdeqkkvreadlvifqfplywfsvpailkgwmdrv
lcqgfafdipgfydsgllqgklallsvttggtaemytktgvngdsryflwplqhgtlhfc
gfkvlapqisfapeiaseeerkgmvaawsqrlqtiwkeepipctahwhfgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3g5mA (A:)
agkkvlivyahqepksfngslknvavdelsrqgctvtvsdlyamnfepratdkditgtls
npevfnygvetheaykqrslasditdeqkkvreadlvifqfplywfsvpailkgwmdrvl
cqgfafdipgfydsgllqgklallsvttggtaemytktgvngdsryflwplqhgtlhfcg
fkvlapqisfapeiaseeerkgmvaawsqrlqtiwkeepipctahwhfgq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3g5mB (B:)
magkkvlivyahqepksfngslknvavdelsrqgctvtvsdlyamnfepratdkditgtl
snpevfnygvetheaykqrslasditdeqkkvreadlvifqfplywfsvpailkgwmdrv
lcqgfafdipgfydsgllqgklallsvttggtaemytktgvngdsryflwplqhgtlhfc
gfkvlapqisfapeiaseeerkgmvaawsqrlqtiwkeepipctahwhfgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3g5mB (B:)
agkkvlivyahqepksfngslknvavdelsrqgctvtvsdlyamnfepratdkditgtls
npevfnygvetheaykqrslasditdeqkkvreadlvifqfplywfsvpailkgwmdrvl
cqgfafdipgfydsgllqgklallsvttggtaemytktgvngdsryflwplqhgtlhfcg
fkvlapqisfapeiaseeerkgmvaawsqrlqtiwkeepipctahwhfgq