PDB entry 3g5k

View 3g5k on RCSB PDB site
Description: Structure and activity of human mitochondrial peptide deformylase, a novel cancer target
Class: hydrolase
Keywords: PEPTIDE DEFORMYLASE, ACTINONIN, Hydrolase, Iron, Metal-binding, Mitochondrion, Protein biosynthesis, Transit peptide
Deposited on 2009-02-05, released 2009-04-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.165
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptide deformylase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PDF, PDF1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HBH1 (3-182)
      • expression tag (0-2)
    Domains in SCOPe 2.05: d3g5ka_
  • Chain 'B':
    Compound: Peptide deformylase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PDF, PDF1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HBH1 (3-182)
      • expression tag (0-2)
    Domains in SCOPe 2.05: d3g5kb_
  • Chain 'C':
    Compound: Peptide deformylase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PDF, PDF1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HBH1 (3-182)
      • expression tag (0-2)
    Domains in SCOPe 2.05: d3g5kc_
  • Chain 'D':
    Compound: Peptide deformylase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PDF, PDF1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HBH1 (3-182)
      • expression tag (0-2)
    Domains in SCOPe 2.05: d3g5kd_
  • Heterogens: BB2, CO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3g5kA (A:)
hmsfshvcqvgdpvlrgvaapveraqlggpelqrltqrlvqvmrrrrcvglsapqlgvpr
qvlalelpealcrecpprqralrqmepfplrvfvnpslrvldsrlvtfpegcesvagfla
cvprfqavqisgldpngeqvvwqasgwaariiqhemdhlqgclfidkmdsrtftnvywmk
vnd

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3g5kB (B:)
hmsfshvcqvgdpvlrgvaapveraqlggpelqrltqrlvqvmrrrrcvglsapqlgvpr
qvlalelpealcrecpprqralrqmepfplrvfvnpslrvldsrlvtfpegcesvagfla
cvprfqavqisgldpngeqvvwqasgwaariiqhemdhlqgclfidkmdsrtftnvywmk
vnd

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3g5kC (C:)
hmsfshvcqvgdpvlrgvaapveraqlggpelqrltqrlvqvmrrrrcvglsapqlgvpr
qvlalelpealcrecpprqralrqmepfplrvfvnpslrvldsrlvtfpegcesvagfla
cvprfqavqisgldpngeqvvwqasgwaariiqhemdhlqgclfidkmdsrtftnvywmk
vnd

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3g5kD (D:)
hmsfshvcqvgdpvlrgvaapveraqlggpelqrltqrlvqvmrrrrcvglsapqlgvpr
qvlalelpealcrecpprqralrqmepfplrvfvnpslrvldsrlvtfpegcesvagfla
cvprfqavqisgldpngeqvvwqasgwaariiqhemdhlqgclfidkmdsrtftnvywmk
vnd