PDB entry 3g4i

View 3g4i on RCSB PDB site
Description: Crystal structure of human phosphodiesterase 4d with d155871
Class: hydrolase
Keywords: phosphodiesterase, PDE4D, Alternative splicing, cAMP, Cytoplasm, Cytoskeleton, Hydrolase, Membrane, Metal-binding, Phosphoprotein
Deposited on 2009-02-03, released 2010-01-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-01-19, with a file datestamp of 2010-01-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.183
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE4D, DPDE3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3g4ia_
  • Chain 'B':
    Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE4D, DPDE3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3g4ib_
  • Chain 'C':
    Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE4D, DPDE3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3g4ic_
  • Chain 'D':
    Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE4D, DPDE3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3g4id_
  • Heterogens: ZN, MG, SO4, D71, EOH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3g4iA (A:)
msiprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfk
ipvdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifa
saihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkq
rqslrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhc
adlsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyi
vhplwetwadlvhpdaqdildtlednrewyqstipqapapapddpeegrqgqtekfqfel
tleedgesdtekdsghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3g4iA (A:)
fgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdt
litylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihd
vdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslr
kmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsn
ptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplw
etwadlvhpdaqdildtlednrewyqstipq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3g4iB (B:)
msiprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfk
ipvdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifa
saihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkq
rqslrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhc
adlsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyi
vhplwetwadlvhpdaqdildtlednrewyqstipqapapapddpeegrqgqtekfqfel
tleedgesdtekdsghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3g4iB (B:)
eqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlityl
mtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhpg
vsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvid
ivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptkpl
qlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwad
lvhpdaqdildtlednrewyqstipq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3g4iC (C:)
msiprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfk
ipvdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifa
saihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkq
rqslrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhc
adlsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyi
vhplwetwadlvhpdaqdildtlednrewyqstipqapapapddpeegrqgqtekfqfel
tleedgesdtekdsghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3g4iC (C:)
teqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlity
lmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhp
gvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvi
divlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptkp
lqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwa
dlvhpdaqdildtlednrewyqstipq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3g4iD (D:)
msiprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfk
ipvdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifa
saihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkq
rqslrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhc
adlsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyi
vhplwetwadlvhpdaqdildtlednrewyqstipqapapapddpeegrqgqtekfqfel
tleedgesdtekdsghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3g4iD (D:)
iprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkip
vdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasa
ihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrq
slrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcad
lsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivh
plwetwadlvhpdaqdildtlednrewyqstipq