PDB entry 3g4c

View 3g4c on RCSB PDB site
Description: Flavine dependant thymidylate syntahse S88C mutant
Class: transferase
Keywords: FTDS; thyx; S88C mutation; dUMP complex, FAD, Flavoprotein, Methyltransferase, Nucleotide biosynthesis, Transferase
Deposited on 2009-02-03, released 2009-04-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.202
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase thyX
    Species: Thermotoga maritima [TaxId:2336]
    Gene: thy1, thyX, TM_0449
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WYT0 (12-End)
      • expression tag (10-11)
      • engineered (99)
    Domains in SCOPe 2.08: d3g4ca1, d3g4ca2
  • Chain 'B':
    Compound: Thymidylate synthase thyX
    Species: Thermotoga maritima [TaxId:2336]
    Gene: thy1, thyX, TM_0449
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WYT0 (12-End)
      • expression tag (11)
      • engineered (99)
    Domains in SCOPe 2.08: d3g4cb1, d3g4cb2
  • Chain 'C':
    Compound: Thymidylate synthase thyX
    Species: Thermotoga maritima [TaxId:2336]
    Gene: thy1, thyX, TM_0449
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WYT0 (12-231)
      • engineered (99)
    Domains in SCOPe 2.08: d3g4cc_
  • Chain 'D':
    Compound: Thymidylate synthase thyX
    Species: Thermotoga maritima [TaxId:2336]
    Gene: thy1, thyX, TM_0449
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WYT0 (12-End)
      • engineered (99)
    Domains in SCOPe 2.08: d3g4cd_
  • Heterogens: FAD, UMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3g4cA (A:)
mgsdkihhhhhhmkidildkgfvelvdvmgndlsavraarvsfdmglkdeerdrhlieyl
mkhghetpfehivftfhvkapifvarqwfrhriasynelcgrysklsyefyipsperleg
ykttippervtekiseivdkayrtyleliesgvprevarivlplnlytrffwtvnarslm
nflnlradshaqweiqqyalaiarifkekcpwtfeaflkyaykgdilkevqv

    Sequence, based on observed residues (ATOM records): (download) 
    >3g4cA (A:)
hhmkidildkgfvelvdvmgndlsavraarvserdrhlieylmkhghetpfehivftfhv
kapifvarqwfrhriasynelcgrysklsyefyipsperlegykttippervtekiseiv
dkayrtyleliesgvprevarivlplnlytrffwtvnarslmnflnlradshaqweiqqy
alaiarifkekcpwtfeaflkyaykgdil

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3g4cB (B:)
mgsdkihhhhhhmkidildkgfvelvdvmgndlsavraarvsfdmglkdeerdrhlieyl
mkhghetpfehivftfhvkapifvarqwfrhriasynelcgrysklsyefyipsperleg
ykttippervtekiseivdkayrtyleliesgvprevarivlplnlytrffwtvnarslm
nflnlradshaqweiqqyalaiarifkekcpwtfeaflkyaykgdilkevqv

    Sequence, based on observed residues (ATOM records): (download) 
    >3g4cB (B:)
hmkidildkgfvelvdvmgndlsavraarvsrdrhlieylmkhghetpfehivftfhvka
pifvarqwfrhriasynelcgrysklsyefyipsperlegykttippervtekiseivdk
ayrtyleliesgvprevarivlplnlytrffwtvnarslmnflnlradshaqweiqqyal
aiarifkekcpwtfeaflkyaykgdilkevq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3g4cC (C:)
mgsdkihhhhhhmkidildkgfvelvdvmgndlsavraarvsfdmglkdeerdrhlieyl
mkhghetpfehivftfhvkapifvarqwfrhriasynelcgrysklsyefyipsperleg
ykttippervtekiseivdkayrtyleliesgvprevarivlplnlytrffwtvnarslm
nflnlradshaqweiqqyalaiarifkekcpwtfeaflkyaykgdilkevqv

    Sequence, based on observed residues (ATOM records): (download) 
    >3g4cC (C:)
mkidildkgfvelvdvmgndlsavraarvsfdeerdrhlieylmkhghetpfehivftfh
vkapifvarqwfrhriasynelcgrysklsyefyipsperlegykttippervtekisei
vdkayrtyleliesgvprevarivlplnlytrffwtvnarslmnflnlradshaqweiqq
yalaiarifkekcpwtfeaflkyaykgdilkevqv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3g4cD (D:)
mgsdkihhhhhhmkidildkgfvelvdvmgndlsavraarvsfdmglkdeerdrhlieyl
mkhghetpfehivftfhvkapifvarqwfrhriasynelcgrysklsyefyipsperleg
ykttippervtekiseivdkayrtyleliesgvprevarivlplnlytrffwtvnarslm
nflnlradshaqweiqqyalaiarifkekcpwtfeaflkyaykgdilkevqv

    Sequence, based on observed residues (ATOM records): (download) 
    >3g4cD (D:)
mkidildkgfvelvdvmgndlsavraarvsferdrhlieylmkhghetpfehivftfhvk
apifvarqwfrhriasynelcgrysklsyefyipsperlegykttippervtekiseivd
kayrtyleliesgvprevarivlplnlytrffwtvnarslmnflnlradshaqweiqqya
laiarifkekcpwtfeaflkyaykgdilkev