PDB entry 3g0x

View 3g0x on RCSB PDB site
Description: Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 5
Class: Oxidoreductase
Keywords: BETA BARREL, TIM Barrel, FAD, Flavoprotein, Membrane, Mitochondrion, Mitochondrion inner membrane, Oxidoreductase, Polymorphism, Pyrimidine biosynthesis, Transit peptide
Deposited on 2009-01-29, released 2009-06-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-06-09, with a file datestamp of 2009-06-05.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.182
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroorotate dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3g0xa_
  • Heterogens: FMN, ORO, MD7, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3g0xA (A:)
matgderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfr
npvgiaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygf
nshglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladyl
vvnvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkedia
svvkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvp
iigvggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtda
igadhrr

    Sequence, based on observed residues (ATOM records): (download) 
    >3g0xA (A:)
derfyaehlmptlqglldpesahrlavrftslgllpfqdsdmlevrvlghkfrnpvgiaa
gfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshglsv
vehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvssp
ntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelg
idglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggv
ssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr