PDB entry 3fzt

View 3fzt on RCSB PDB site
Description: Crystal structure of PYK2 complexed with PF-4618433
Class: transferase
Keywords: PYK2, Kinase, DFG, Alternative splicing, ATP-binding, Cell membrane, Cytoplasm, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Transferase, Tyrosine-protein kinase
Deposited on 2009-01-26, released 2009-03-31
The last revision prior to the SCOPe 2.05 freeze date was dated 2010-01-19, with a file datestamp of 2010-01-15.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.198
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein tyrosine kinase 2 beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3fzta_
  • Heterogens: 4JZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fztA (A:)
pqygiaredvvlnrilgegffgevyegvytnhkgekinvavktckkdctldnkekfmsea
vimknldhphivkligiieeeptwiimelypygelghylernknslkvltlvlyslqick
amaylesincvhrdiavrnilvaspecvklgdfglsryiededyykasvtrlpikwmspe
sinfrrfttasdvwmfavcmweilsfgkqpffwlenkdvigvlekgdrlpkpdlcppvly
tlmtrcwdydpsdrprftelvcslsdvyqmekdiame

    Sequence, based on observed residues (ATOM records): (download) 
    >3fztA (A:)
iaredvvlnrilgegffgevyegvytnhkgekinvavktckkdctldnkekfmseavimk
nldhphivkligiieeeptwiimelypygelghylernknslkvltlvlyslqickamay
lesincvhrdiavrnilvaspecvklgdfglsrdelpikwmspesinfrrfttasdvwmf
avcmweilsfgkqpffwlenkdvigvlekgdrlpkpdlcppvlytlmtrcwdydpsdrpr
ftelvcslsdvyqmekdia