PDB entry 3fzr

View 3fzr on RCSB PDB site
Description: Crystal structure of PYK2 complexed with PF-431396
Class: transferase
Keywords: PYK2, Kinase, DFG, Alternative splicing, ATP-binding, Cell membrane, Cytoplasm, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Transferase, Tyrosine-protein kinase
Deposited on 2009-01-26, released 2009-03-31
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-01-19, with a file datestamp of 2010-01-15.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.214
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein tyrosine kinase 2 beta
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3fzra_
  • Heterogens: 3JZ, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3fzrA (A:)
    pqygiaredvvlnrilgegffgevyegvytnhkgekinvavktckkdctldnkekfmsea
    vimknldhphivkligiieeeptwiimelypygelghylernknslkvltlvlyslqick
    amaylesincvhrdiavrnilvaspecvklgdfglsryiededyykasvtrlpikwmspe
    sinfrrfttasdvwmfavcmweilsfgkqpffwlenkdvigvlekgdrlpkpdlcppvly
    tlmtrcwdydpsdrprftelvcslsdvyqmekdiame
    

    Sequence, based on observed residues (ATOM records): (download)
    >3fzrA (A:)
    giaredvvlnrilgegffgevyegvytnhkgekinvavktckkdctldnkekfmseavim
    knldhphivkligiieeeptwiimelypygelghylernknslkvltlvlyslqickama
    ylesincvhrdiavrnilvaspecvklgdfglsrtrlpikwmspesinfrrfttasdvwm
    favcmweilsfgkqpffwlenkdvigvlekgdrlpkpdlcppvlytlmtrcwdydpsdrp
    rftelvcslsdvyqmekdiam