PDB entry 3fxz

View 3fxz on RCSB PDB site
Description: Crystal structure of PAK1 kinase domain with ruthenium complex lambda-FL172
Class: Transferase
Keywords: Transferase, Kinase, ATP-binding, Phosphorylation, Allosteric enzyme, Alternative splicing, Apoptosis, Cell junction, Cytoplasm, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase
Deposited on 2009-01-21, released 2009-02-17
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-17, with a file datestamp of 2009-02-13.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: 0.196
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PAK 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13153 (0-End)
      • engineered (50)
    Domains in SCOPe 2.05: d3fxza_
  • Heterogens: FLL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fxzA (A:)
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpk
keliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaa
vcreclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtp
ywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpe
klsaifrdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeatknnh

    Sequence, based on observed residues (ATOM records): (download) 
    >3fxzA (A:)
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpk
keliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaa
vcreclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtp
ywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpe
klsaifrdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeat