PDB entry 3fxi

View 3fxi on RCSB PDB site
Description: crystal structure of the human tlr4-human md-2-e.coli lps ra complex
Deposited on 2009-01-21, released 2009-03-03
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toll-like receptor 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Tlr4
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Toll-like receptor 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Tlr4
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Lymphocyte antigen 96
    Species: Homo sapiens [TaxId:9606]
    Gene: ESOP1, LY96, MD-2, MD2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Lymphocyte antigen 96
    Species: Homo sapiens [TaxId:9606]
    Gene: ESOP1, LY96, MD-2, MD2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FTT, DAO, MYR, PO4, NAG, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3fxiA (A:)
epcvevvpnityqcmelnfykipdnlpfstknldlsfnplrhlgsysffsfpelqvldls
rceiqtiedgayqslshlstliltgnpiqslalgafsglsslqklvavetnlaslenfpi
ghlktlkelnvahnliqsfklpeyfsnltnlehldlssnkiqsiyctdlrvlhqmpllnl
sldlslnpmnfiqpgafkeirlhkltlrnnfdslnvmktciqglaglevhrlvlgefrne
gnlekfdksaleglcnltieefrlayldyylddiidlfncltnvssfslvsvtiervkdf
synfgwqhlelvnckfgqfptlklkslkrltftsnkggnafsevdlpslefldlsrngls
fkgccsqsdfgttslkyldlsfngvitmssnflgleqlehldfqhsnlkqmsefsvflsl
rnliyldishthtrvafngifnglsslevlkmagnsfqenflpdiftelrnltfldlsqc
qleqlsptafnslsslqvlnmshnnffsldtfpykclnslqvldyslnhimtskkqelqh
fpsslaflnltqndfactcehqsflqwikdqrqllvevermecatpsdkqgmpvlslnit
cqmnk

    Sequence, based on observed residues (ATOM records):
    >3fxiA (A:)
epcvevvpnityqcmelnfykipdnlpfstknldlsfnplrhlgsysffsfpelqvldls
rceiqtiedgayqslshlstliltgnpiqslalgafsglsslqklvavetnlaslenfpi
ghlktlkelnvahnliqsfklpeyfsnltnlehldlssnkiqsiyctdlrvlhqmpllnl
sldlslnpmnfiqpgafkeirlhkltlrnnfdslnvmktciqglaglevhrlvlgefrne
gnlekfdksaleglcnltieefrlayldyylddiidlfncltnvssfslvsvtiervkdf
synfgwqhlelvnckfgqfptlklkslkrltftsnkggnafsevdlpslefldlsrngls
fkgccsqsdfgttslkyldlsfngvitmssnflgleqlehldfqhsnlkqmsefsvflsl
rnliyldishthtrvafngifnglsslevlkmagnsfqenflpdiftelrnltfldlsqc
qleqlsptafnslsslqvlnmshnnffsldtfpykclnslqvldyslnhimtskkqelqh
fpsslaflnltqndfactcehqsflqwikdqrqllvevermecatpsdkqgmpvlslnit
c

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3fxiB (B:)
epcvevvpnityqcmelnfykipdnlpfstknldlsfnplrhlgsysffsfpelqvldls
rceiqtiedgayqslshlstliltgnpiqslalgafsglsslqklvavetnlaslenfpi
ghlktlkelnvahnliqsfklpeyfsnltnlehldlssnkiqsiyctdlrvlhqmpllnl
sldlslnpmnfiqpgafkeirlhkltlrnnfdslnvmktciqglaglevhrlvlgefrne
gnlekfdksaleglcnltieefrlayldyylddiidlfncltnvssfslvsvtiervkdf
synfgwqhlelvnckfgqfptlklkslkrltftsnkggnafsevdlpslefldlsrngls
fkgccsqsdfgttslkyldlsfngvitmssnflgleqlehldfqhsnlkqmsefsvflsl
rnliyldishthtrvafngifnglsslevlkmagnsfqenflpdiftelrnltfldlsqc
qleqlsptafnslsslqvlnmshnnffsldtfpykclnslqvldyslnhimtskkqelqh
fpsslaflnltqndfactcehqsflqwikdqrqllvevermecatpsdkqgmpvlslnit
cqmnk

    Sequence, based on observed residues (ATOM records):
    >3fxiB (B:)
epcvevvpnityqcmelnfykipdnlpfstknldlsfnplrhlgsysffsfpelqvldls
rceiqtiedgayqslshlstliltgnpiqslalgafsglsslqklvavetnlaslenfpi
ghlktlkelnvahnliqsfklpeyfsnltnlehldlssnkiqsiyctdlrvlhqmpllnl
sldlslnpmnfiqpgafkeirlhkltlrnnfdslnvmktciqglaglevhrlvlgefrne
gnlekfdksaleglcnltieefrlayldyylddiidlfncltnvssfslvsvtiervkdf
synfgwqhlelvnckfgqfptlklkslkrltftsnkggnafsevdlpslefldlsrngls
fkgccsqsdfgttslkyldlsfngvitmssnflgleqlehldfqhsnlkqmsefsvflsl
rnliyldishthtrvafngifnglsslevlkmagnsfqenflpdiftelrnltfldlsqc
qleqlsptafnslsslqvlnmshnnffsldtfpykclnslqvldyslnhimtskkqelqh
fpsslaflnltqndfactcehqsflqwikdqrqllvevermecatpsdkqgmpvlslnit
c

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3fxiC (C:)
qkqywvcnssdasisytycdkmqypisinvnpcielkgskgllhifyiprrdlkqlyfnl
yitvntmnlpkrkevicrgsdddysfcralkgetvnttisfsfkgikfskgkykcvveai
sgspeemlfclefvilhqpnsn

    Sequence, based on observed residues (ATOM records):
    >3fxiC (C:)
qkqywvcnssdasisytycdkmqypisinvnpcielkgskgllhifyiprrdlkqlyfnl
yitvntmnlpkrkevicrgsdddysfcralkgetvnttisfsfkgikfskgkykcvveai
sgspeemlfclefvilhqpn

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3fxiD (D:)
qkqywvcnssdasisytycdkmqypisinvnpcielkgskgllhifyiprrdlkqlyfnl
yitvntmnlpkrkevicrgsdddysfcralkgetvnttisfsfkgikfskgkykcvveai
sgspeemlfclefvilhqpnsn

    Sequence, based on observed residues (ATOM records):
    >3fxiD (D:)
qkqywvcnssdasisytycdkmqypisinvnpcielkgskgllhifyiprrdlkqlyfnl
yitvntmnlpkrkevicrgsdddysfcralkgetvnttisfsfkgikfskgkykcvveai
sgspeemlfclefvilhqpn