PDB entry 3fv3

View 3fv3 on RCSB PDB site
Description: Secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A
Class: hydrolase
Keywords: pepstatin A, secreted aspartic protease, virulence factor, HYDROLASE
Deposited on 2009-01-15, released 2009-05-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.166
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sapp1p-secreted aspartic protease 1
    Species: Candida parapsilosis [TaxId:5480]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-338)
    Domains in SCOPe 2.06: d3fv3a_
  • Chain 'B':
    Compound: Sapp1p-secreted aspartic protease 1
    Species: Candida parapsilosis [TaxId:5480]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-338)
    Domains in SCOPe 2.06: d3fv3b_
  • Chain 'C':
    Compound: Sapp1p-secreted aspartic protease 1
    Species: Candida parapsilosis [TaxId:5480]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-338)
    Domains in SCOPe 2.06: d3fv3c_
  • Chain 'D':
    Compound: Sapp1p-secreted aspartic protease 1
    Species: Candida parapsilosis [TaxId:5480]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-338)
    Domains in SCOPe 2.06: d3fv3d_
  • Chain 'E':
    Compound: Sapp1p-secreted aspartic protease 1
    Species: Candida parapsilosis [TaxId:5480]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-338)
    Domains in SCOPe 2.06: d3fv3e_
  • Chain 'F':
    Compound: Sapp1p-secreted aspartic protease 1
    Species: Candida parapsilosis [TaxId:5480]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-338)
    Domains in SCOPe 2.06: d3fv3f_
  • Chain 'G':
    Compound: Sapp1p-secreted aspartic protease 1
    Species: Candida parapsilosis [TaxId:5480]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-338)
    Domains in SCOPe 2.06: d3fv3g_
  • Chain 'H':
    Compound: Sapp1p-secreted aspartic protease 1
    Species: Candida parapsilosis [TaxId:5480]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-338)
    Domains in SCOPe 2.06: d3fv3h_
  • Chain 'I':
    Compound: pepstatin A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-5)
  • Chain 'J':
    Compound: pepstatin A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-5)
  • Chain 'K':
    Compound: pepstatin A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-5)
  • Chain 'L':
    Compound: pepstatin A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-5)
  • Chain 'M':
    Compound: pepstatin A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-5)
  • Chain 'N':
    Compound: pepstatin A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-5)
  • Chain 'O':
    Compound: pepstatin A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-5)
  • Chain 'P':
    Compound: pepstatin A
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3FV3 (0-5)
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3fv3A (A:)
dsislslinegpsyaskvsvgsnkqqqtviidtgssdfwvvdsnaqcgkgvdckssgtft
psssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgi
gytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdna
kysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladka
garlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsd
dtilgdnflrhayllynldantisiaqvkyttdssisav

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3fv3B (B:)
dsislslinegpsyaskvsvgsnkqqqtviidtgssdfwvvdsnaqcgkgvdckssgtft
psssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgi
gytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdna
kysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladka
garlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsd
dtilgdnflrhayllynldantisiaqvkyttdssisav

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3fv3C (C:)
dsislslinegpsyaskvsvgsnkqqqtviidtgssdfwvvdsnaqcgkgvdckssgtft
psssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgi
gytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdna
kysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladka
garlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsd
dtilgdnflrhayllynldantisiaqvkyttdssisav

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3fv3D (D:)
dsislslinegpsyaskvsvgsnkqqqtviidtgssdfwvvdsnaqcgkgvdckssgtft
psssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgi
gytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdna
kysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladka
garlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsd
dtilgdnflrhayllynldantisiaqvkyttdssisav

    Sequence, based on observed residues (ATOM records): (download) 
    >3fv3D (D:)
dsislslinegpsyaskvsvgsnkqqtviidtgssdfwvvdsnaqcgkgvdckssgtftp
sssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgig
ytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdnak
ysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladkag
arlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsdd
tilgdnflrhayllynldantisiaqvkyttdssisav

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3fv3E (E:)
dsislslinegpsyaskvsvgsnkqqqtviidtgssdfwvvdsnaqcgkgvdckssgtft
psssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgi
gytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdna
kysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladka
garlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsd
dtilgdnflrhayllynldantisiaqvkyttdssisav

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3fv3F (F:)
dsislslinegpsyaskvsvgsnkqqqtviidtgssdfwvvdsnaqcgkgvdckssgtft
psssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgi
gytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdna
kysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladka
garlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsd
dtilgdnflrhayllynldantisiaqvkyttdssisav

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3fv3G (G:)
dsislslinegpsyaskvsvgsnkqqqtviidtgssdfwvvdsnaqcgkgvdckssgtft
psssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgi
gytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdna
kysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladka
garlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsd
dtilgdnflrhayllynldantisiaqvkyttdssisav

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3fv3H (H:)
dsislslinegpsyaskvsvgsnkqqqtviidtgssdfwvvdsnaqcgkgvdckssgtft
psssssyknlgaaftirygdgstsqgtwgkdtvtingvsitgqqiadvtqtsvdqgilgi
gytsneavydtsgrqttpnydnvpvtlkkqgkirtnayslylnspsaetgtiifggvdna
kysgklvaeqvtssqaltislasvnlkgssfsfgdgalldsgttltyfpsdfaaqladka
garlvqvardqylyfidcntdtsgttvfnfgngakitvpnteyvyqngdgtclwgiqpsd
dtilgdnflrhayllynldantisiaqvkyttdssisav

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.