PDB entry 3ful

View 3ful on RCSB PDB site
Description: Leukotriene A4 hydrolase in complex with pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone
Class: hydrolase/hydrolase inhibitor
Keywords: Leukotriene A4 Hydrolase, LTA4H, Fragment crystallography, Fragments of Life, FOL, Hydrolase-hydrolase inhibitor complex, Leukotriene biosynthesis, Metal-binding, Metalloprotease, Multifunctional enzyme, Protease
Deposited on 2009-01-14, released 2010-01-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fula1, d3fula2, d3fula3
  • Heterogens: ZN, YB, 52D, IMD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3fulA (A:)
    mpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdl
    tiekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwlt
    peqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetp
    dpedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetes
    mlkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheish
    swtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfget
    hpftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksi
    ttddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitak
    eddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwl
    rlciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvt
    amlvgkdlkvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >3fulA (A:)
    dtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdltiekv
    vingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltpeqts
    gkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpdpedp
    srkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesmlkia
    edlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishswtgn
    lvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgethpftk
    lvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksittddw
    kdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitakeddln
    sfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlrlciq
    skwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvtamlvg
    kdlkv