PDB entry 3fui

View 3fui on RCSB PDB site
Description: Leukotriene A4 hydrolase in complex with N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline
Class: hydrolase
Keywords: Leukotriene A4 Hydrolase, LTA4H, Fragment crystallography, Fragments of Life, FOL, Alternative splicing, Cytoplasm, Hydrolase, Leukotriene biosynthesis, Metal-binding, Metalloprotease, Multifunctional enzyme, Polymorphism, Protease, Zinc
Deposited on 2009-01-14, released 2009-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fuia1, d3fuia2, d3fuia3
  • Heterogens: YB, ZN, 812, IMD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3fuiA (A:)
    mpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdl
    tiekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwlt
    peqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetp
    dpedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetes
    mlkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheish
    swtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfget
    hpftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksi
    ttddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitak
    eddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwl
    rlciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvt
    amlvgkdlkvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >3fuiA (A:)
    dtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdltiekv
    vingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltpeqts
    gkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpdpedp
    srkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesmlkia
    edlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishswtgn
    lvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgethpftk
    lvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksittddw
    kdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitakeddln
    sfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlrlciq
    skwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvtamlvg
    kdlkvd