PDB entry 3ftx

View 3ftx on RCSB PDB site
Description: Leukotriene A4 hydrolase in complex with dihydroresveratrol and bestatin
Class: hydrolase
Keywords: Leukotriene A4 Hydrolase, LTA4H, Fragment crystallography, Fragments of Life, FOL, Alternative splicing, Cytoplasm, Hydrolase, Leukotriene biosynthesis, Metal-binding, Metalloprotease, Multifunctional enzyme, Polymorphism, Protease, Zinc
Deposited on 2009-01-13, released 2009-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-09-15, with a file datestamp of 2009-09-11.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: 0.172
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ftxa1, d3ftxa2, d3ftxa3
  • Heterogens: ZN, YB, RE2, BES, ACT, IMD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ftxA (A:)
mpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdl
tiekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwlt
peqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetp
dpedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetes
mlkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheish
swtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfget
hpftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksi
ttddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitak
eddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwl
rlciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvt
amlvgkdlkvd

    Sequence, based on observed residues (ATOM records): (download) 
    >3ftxA (A:)
vdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdltiek
vvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltpeqt
sgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpdped
psrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesmlki
aedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishswtg
nlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgethpft
klvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksittdd
wkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitakeddl
nsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlrlci
qskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvtamlv
gkdlkvd