PDB entry 3fr0

View 3fr0 on RCSB PDB site
Description: Human glucokinase in complex with 2-amino benzamide activator
Class: transferase
Keywords: Hexokinase IV, Allosteric enzyme, Diabetes, Alternative splicing, ATP-binding, Diabetes mellitus, Disease mutation, Glycolysis, Kinase, Nucleotide-binding, Polymorphism, Transferase
Deposited on 2009-01-08, released 2009-02-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fr0a1, d3fr0a2, d3fr0a3
  • Heterogens: GLC, AJB, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fr0A (A:)
taltlveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegse
vgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyiseci
sdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaik
rrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegr
mcvntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlv
denllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrra
cesvstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrl
tpsceitfieseegsgrgaalvsavackkacmlgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3fr0A (A:)
tlveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegsevgd
flsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyisecisdf
ldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaikrrg
dfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegrmcv
ntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlvden
llfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrraces
vstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrltps
ceitfieseegsgrgaalvsavackkac