PDB entry 3fqw
View 3fqw on RCSB PDB site
Description: Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
Class: immune system
Keywords: IMMUNE SYSTEM, PHOSPHORYLATION, Glycoprotein, Immune response, Membrane, MHC I, Phosphoprotein, Polymorphism, Transmembrane, Ubl conjugation, Disease mutation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, cancer, TCR, self-epitope
Deposited on
2009-01-07, released
2009-03-03
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-03-10, with a file datestamp of
2009-03-06.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: 0.17
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3fqwb_ - Chain 'C':
Compound: peptide 1097-1105 from insulin receptor substrate 2 (IRS2): RVASPTSGV
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: CD, CO, HOH