PDB entry 3fof

View 3fof on RCSB PDB site
Description: Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases
Deposited on 2008-12-30, released 2009-02-24
The last revision was dated 2009-06-23, with a file datestamp of 2009-06-19.
Experiment type: XRAY
Resolution: 4 Å
R-factor: 0.244
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA topoisomerase 4 subunit A
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: parC, SP_0855
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA topoisomerase 4 subunit A
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: parC, SP_0855
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA topoisomerase 4 subunit B
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: parE, SP_0852
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA topoisomerase 4 subunit B
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: parE, SP_0852
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA (5'-d(p*ap*cp*cp*ap*ap*gp*gp*tp*cp*ap*tp*gp*ap*ap*t)-3')
  • Chain 'F':
    Compound: DNA (5'-d(p*ap*gp*tp*cp*ap*tp*tp*cp*ap*tp*gp*ap*cp*cp*tp*tp*gp*gp*t)-3')
  • Chain 'G':
    Compound: DNA (5'-d(p*cp*tp*gp*tp*tp*tp*tp*ap*cp*gp*tp*gp*cp*ap*t)-3')
  • Chain 'H':
    Compound: DNA (5'-d(p*gp*ap*cp*tp*ap*tp*gp*cp*ap*cp*gp*tp*ap*ap*ap*ap*cp*ap*g)-3')
  • Heterogens: MFX

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3fofA (A:)
msniqnmsledimgerfgryskyiiqdralpdirdglkpvqrrilysmnkdsntfdksyr
ksaksvgnimgnfhphgdssiydamvrmsqnwknreilvemhgnngsmdgdppaamryte
arlseiagyllqdiekktvpfawnfddtekeptvlpaafpnllvngstgisagyatdipp
hnlaevidaavymidhptakidklmeflpgpdfptgaiiqgrdeikkayetgkgrvvvrs
kteieklkggkeqiviteipyeinkanlvkkiddvrvnnkvagiaevrdesdrdglriai
elkkdantelvlnylfkytdlqinynfnmvaidnftprqvgivpilssyiahrrevilar
srfdkekaekrlhiveglirvisildevialirasenkadakenlkvsydfteeqaeaiv
tlqlyrltntdvvvlqeeeaelrekiamlaaiigdertmynlmkkelrevkkkfatprls
sledtakalehhhhhh

    Sequence, based on observed residues (ATOM records):
    >3fofA (A:)
qnmsledimgerfgryskyiiqdralpdirdglkpvqrrilysmnkdsndksyrksaksv
gnimgnfhphgdssiydamvrmsqnwknreilvemhgnngsmdgdppaamrytearlsei
agyllqdiekktvpfawnfddtekeptvlpaafpnllvntdipphnlaevidaavymidh
ptakidklmeflpgpdfptgaiiqgrdeikkayetggrvvvrskteieklkggkeqivit
einkanlvkkiddvrvnnkvieltelvlnylfkytdlqinynfnmvaidnftprqvgivp
ilssyiahrrevilarsrfdkekaekrlhiveglirvisildevialirasenkadaken
lkvsydfteeqaeaivtlqlyrltntdvvvlqeeeaelrekiamlaaiigdertmynlmk
kelrevkkkfatprl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3fofB (B:)
msniqnmsledimgerfgryskyiiqdralpdirdglkpvqrrilysmnkdsntfdksyr
ksaksvgnimgnfhphgdssiydamvrmsqnwknreilvemhgnngsmdgdppaamryte
arlseiagyllqdiekktvpfawnfddtekeptvlpaafpnllvngstgisagyatdipp
hnlaevidaavymidhptakidklmeflpgpdfptgaiiqgrdeikkayetgkgrvvvrs
kteieklkggkeqiviteipyeinkanlvkkiddvrvnnkvagiaevrdesdrdglriai
elkkdantelvlnylfkytdlqinynfnmvaidnftprqvgivpilssyiahrrevilar
srfdkekaekrlhiveglirvisildevialirasenkadakenlkvsydfteeqaeaiv
tlqlyrltntdvvvlqeeeaelrekiamlaaiigdertmynlmkkelrevkkkfatprls
sledtakalehhhhhh

    Sequence, based on observed residues (ATOM records):
    >3fofB (B:)
qnmsledimgerfgryskyiiqdralpdirdglkpvqrrilysmnkdsndksyrksaksv
gnimgnfhphgdssiydamvrmsqnwknreilvemhgnngsmdgdppaamrytearlsei
agyllqdiekktvpfawnfddtekeptvlpaafpnllvntdipphnlaevidaavymidh
ptakidklmeflpgpdfptgaiiqgrdeikkayetgkgrvvvrseieklkggkeqivite
inkanlvkkiddvrvnnkielntelvlnylfkytdlqinfnmvaidnftprqvgivpils
syiahrrevilarsrfdkekaekrlhiveglirvisildevialirasenkadakenlkv
sydfteeqaeaivtlqlyrltntdvvvlqeeeaelrekiamlaaiigdertmynlmkkel
revkkkfatprl

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3fofC (C:)
mghhhhhhhhhhssghiddddkhmknkkdkgllsgkltpaqsknpaknelylvegdsagg
sakqgrdrkfqailplrgkvintakakmadilkneeintmiytigagvgadfsiedanyd
kiiimtdadtdgahiqtllltffyrymrplveaghvyialpplykmskgkgkkeevayaw
tdgeleelrkqfgkgatlqrykglgemnadqlwettmnpetrtlirvtiedlaraerrvn
vlmgdkveprrkwiednvkftleeatvf

    Sequence, based on observed residues (ATOM records):
    >3fofC (C:)
tpaqsnpaknelylvegdsaggsakqdrkfilplrgkvintakakmadilkneeintmiy
tigagvgkiiimtdadtdgahiqtllltffyrymrplveaghvyialpplykmskgkgkk
eevaawtdgeleelkgatlqrykglgemdqlwettmnpetrtlirvtiedlaraerrvnv
lmgdkveprrkwiedn

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3fofD (D:)
mghhhhhhhhhhssghiddddkhmknkkdkgllsgkltpaqsknpaknelylvegdsagg
sakqgrdrkfqailplrgkvintakakmadilkneeintmiytigagvgadfsiedanyd
kiiimtdadtdgahiqtllltffyrymrplveaghvyialpplykmskgkgkkeevayaw
tdgeleelrkqfgkgatlqrykglgemnadqlwettmnpetrtlirvtiedlaraerrvn
vlmgdkveprrkwiednvkftleeatvf

    Sequence, based on observed residues (ATOM records):
    >3fofD (D:)
tpaqsnpaknelylvegdsaggsakqgrdrkfilplrvintakakmadilkneeintmiy
tigagvgkiiimtdadtdgahiqtllltffyrymrplveaghvyialpplykmskgkgkk
eevayawtdgeleelkgatlqrykglgemnadqlwettmnpetrtlirvtiedlaraerr
vnvlmgdkveprrkwiedn

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.