PDB entry 3fmi

View 3fmi on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase complexed with 7-Keto 8-aminopelargonic acid
Deposited on 2008-12-22, released 2009-06-30
The last revision was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 2.18 Å
R-factor: 0.216
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dethiobiotin synthetase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: bioD, MT1621, MTCY336.33c, Rv1570
    Database cross-references and differences (RAF-indexed):
    • Uniprot O06620 (25-250)
      • expression tag (20-24)
  • Chain 'B':
    Compound: dethiobiotin synthetase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: bioD, MT1621, MTCY336.33c, Rv1570
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: dethiobiotin synthetase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: bioD, MT1621, MTCY336.33c, Rv1570
    Database cross-references and differences (RAF-indexed):
    • Uniprot O06620 (25-End)
      • expression tag (23-24)
  • Chain 'D':
    Compound: dethiobiotin synthetase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: bioD, MT1621, MTCY336.33c, Rv1570
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, KAP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3fmiA (A:)
mgsshhhhhhssglqgtenlyfqshmtilvvtgtgtgvgktvvcaalasaarqagidvav
ckpvqtgtargdddlaevgrlagvtqlaglarypqpmapaaaaehagmalpardqivrli
adldrpgrltlvegaggllvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlea
laaqqvscaglvigswpdppglvaasnrsalariamvraalpagaasldagdfaamsaaa
fdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >3fmiA (A:)
yfqshmtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgr
lagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllv
elaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdpp
glvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3fmiB (B:)
mgsshhhhhhssglqgtenlyfqshmtilvvtgtgtgvgktvvcaalasaarqagidvav
ckpvqtgtargdddlaevgrlagvtqlaglarypqpmapaaaaehagmalpardqivrli
adldrpgrltlvegaggllvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlea
laaqqvscaglvigswpdppglvaasnrsalariamvraalpagaasldagdfaamsaaa
fdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >3fmiB (B:)
tilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlagvtq
laglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvelaepg
vtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglvaas
nrsalariamvraalpagaasldagdfaamsaaafdrnwvaglv

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3fmiC (C:)
mgsshhhhhhssglqgtenlyfqshmtilvvtgtgtgvgktvvcaalasaarqagidvav
ckpvqtgtargdddlaevgrlagvtqlaglarypqpmapaaaaehagmalpardqivrli
adldrpgrltlvegaggllvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlea
laaqqvscaglvigswpdppglvaasnrsalariamvraalpagaasldagdfaamsaaa
fdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >3fmiC (C:)
shmtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlag
vtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvela
epgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglv
aasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3fmiD (D:)
mgsshhhhhhssglqgtenlyfqshmtilvvtgtgtgvgktvvcaalasaarqagidvav
ckpvqtgtargdddlaevgrlagvtqlaglarypqpmapaaaaehagmalpardqivrli
adldrpgrltlvegaggllvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlea
laaqqvscaglvigswpdppglvaasnrsalariamvraalpagaasldagdfaamsaaa
fdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >3fmiD (D:)
tilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlagvtq
laglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvelaepg
vtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglvaas
nrsalariamvraalpagaasldagdfaamsaaafdrnwvaglv