PDB entry 3flo

View 3flo on RCSB PDB site
Description: Crystal structure of the carboxyl-terminal domain of yeast DNA polymerase alpha in complex with its B subunit
Deposited on 2008-12-19, released 2009-06-09
The last revision was dated 2012-09-05, with a file datestamp of 2012-08-31.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.192
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase alpha subunit B
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL12
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA polymerase alpha catalytic subunit A
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL1, CDC17
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA polymerase alpha subunit B
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL12
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA polymerase alpha catalytic subunit A
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL1, CDC17
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA polymerase alpha subunit B
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL12
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: DNA polymerase alpha catalytic subunit A
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL1, CDC17
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: DNA polymerase alpha subunit B
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL12
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: DNA polymerase alpha catalytic subunit A
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL1, CDC17
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: DNA polymerase alpha catalytic subunit A
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL1, CDC17
    Database cross-references and differences (RAF-indexed):
    • PDB 3FLO (0-2)
  • Chain 'J':
    Compound: DNA polymerase alpha catalytic subunit A
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL1, CDC17
    Database cross-references and differences (RAF-indexed):
    • PDB 3FLO (0-2)
  • Chain 'K':
    Compound: DNA polymerase alpha catalytic subunit A
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL1, CDC17
    Database cross-references and differences (RAF-indexed):
    • PDB 3FLO (0-2)
  • Chain 'L':
    Compound: DNA polymerase alpha catalytic subunit A
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: POL1, CDC17
    Database cross-references and differences (RAF-indexed):
    • PDB 3FLO (0-2)
  • Heterogens: SO4, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3floA (A:)
kfrtmrqnlqeasdvlddqiesftkiiqnhyklspndfadptiqsqseiyavgrivpdsp
tydkflnpeslsletsrmggvgrrvrldlsqvnelsfflgqivafkgknangdyftvnsi
lplpypnspvstsqelqefqanlegsslkvivtcgpyfandnfslellqefidsinnevk
phvlimfgpfidithpliasgklpnfpqfktqpktldelflklftpilktisphiqtvli
pstkdaisnhaaypqaslirkalqlpkrnfkcmanpssfqineiyfgcsnvdtfkdlkev
ikggttssryrldrvsehilqqrryypifpgsirtrikpkdvstkketndmeskeekvye
hisgadldvsylgltefvggfspdimiipselqhfarvvqnvvvinpgrfiratgnrgsy
aqitvqcpdledgkltlvegeepvylhnvwkrarvdlias

    Sequence, based on observed residues (ATOM records):
    >3floA (A:)
rtmrqnlqeasdvlddqiesftkiiqnhyklspndfadptiqsqseiyavgrivpdspty
dkflnpeslsletsrmggvgrrvrldlsqvnelsfflgqivafkgknangdyftvnsilp
lpypnspvstsqelqefqanlegsslkvivtcgpyfandnfslellqefidsinnevkph
vlimfgpfidithpliasgklpnfpqfktqpktldelflklftpilktisphiqtvlips
tkdaisnhaaypqaslirkalqlpkrnfkcmanpssfqineiyfgcsnvdtfkdlkevik
ggttssryrldrvsehilqqrryypifpgsirthisgadldvsylgltefvggfspdimi
ipselqhfarvvqnvvvinpgrfiratgnrgsyaqitvqcpdledgkltlvegeepvylh
nvwkrarvdlias

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3floB (B:)
nlqplettitdverfkdtvtlelscpscdkrfpfggivssnyyrvsynglqckhceqlft
plqltsqiehsirahislyyagwlqcddstcgivtrqvsvfgkrclndgctgvmrykysd
kqlynqllyfdslfdceknkkqelkpiylpddldypkeqltessikalteqnrelmetgr
svvqkylndcgrryvdmtsifdfmln

    Sequence, based on observed residues (ATOM records):
    >3floB (B:)
dverfkdtvtlelscpscdkrfpfggivssnyyrvsynglqckhceqlftplqltsqieh
sirahislyyagwlqcddstcgivtrqvsvfgkrclndgctgvmrykysdkqlynqllyf
dslfdceknkkqelkpiylpddldypkeqltessikalteqnrelmetgrsvvqkylndc

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3floC (C:)
kfrtmrqnlqeasdvlddqiesftkiiqnhyklspndfadptiqsqseiyavgrivpdsp
tydkflnpeslsletsrmggvgrrvrldlsqvnelsfflgqivafkgknangdyftvnsi
lplpypnspvstsqelqefqanlegsslkvivtcgpyfandnfslellqefidsinnevk
phvlimfgpfidithpliasgklpnfpqfktqpktldelflklftpilktisphiqtvli
pstkdaisnhaaypqaslirkalqlpkrnfkcmanpssfqineiyfgcsnvdtfkdlkev
ikggttssryrldrvsehilqqrryypifpgsirtrikpkdvstkketndmeskeekvye
hisgadldvsylgltefvggfspdimiipselqhfarvvqnvvvinpgrfiratgnrgsy
aqitvqcpdledgkltlvegeepvylhnvwkrarvdlias

    Sequence, based on observed residues (ATOM records):
    >3floC (C:)
rtmrqnlqeasdvlddqiesftkiiqnhyklspndfadptiqsqseiyavgrivpdspty
dkflnpeslsletsrmggvgrrvrldlsqvnelsfflgqivafkgknangdyftvnsilp
lpypnspvstsqelqefqanlegsslkvivtcgpyfandnfslellqefidsinnevkph
vlimfgpfidithpliasgklpnfpqfktqpktldelflklftpilktisphiqtvlips
tkdaisnhaaypqaslirkalqlpkrnfkcmanpssfqineiyfgcsnvdtfkdlkevik
ggttssryrldrvsehilqqrryypifpgsirthisgadldvsylgltefvggfspdimi
ipselqhfarvvqnvvvinpgrfiratgnrgsyaqitvqcpdledgkltlvegeepvylh
nvwkrarvdlias

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3floD (D:)
nlqplettitdverfkdtvtlelscpscdkrfpfggivssnyyrvsynglqckhceqlft
plqltsqiehsirahislyyagwlqcddstcgivtrqvsvfgkrclndgctgvmrykysd
kqlynqllyfdslfdceknkkqelkpiylpddldypkeqltessikalteqnrelmetgr
svvqkylndcgrryvdmtsifdfmln

    Sequence, based on observed residues (ATOM records):
    >3floD (D:)
dverfkdtvtlelscpscdkrfpfggivssnyyrvsynglqckhceqlftplqltsqieh
sirahislyyagwlqcddstcgivtrqvsvfgkrclndgctgvmrykysdkqlynqllyf
dslfdceknkkqelkpiylpddldypkeqltessikalteqnrelmetgrsvvqkylndc

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3floE (E:)
kfrtmrqnlqeasdvlddqiesftkiiqnhyklspndfadptiqsqseiyavgrivpdsp
tydkflnpeslsletsrmggvgrrvrldlsqvnelsfflgqivafkgknangdyftvnsi
lplpypnspvstsqelqefqanlegsslkvivtcgpyfandnfslellqefidsinnevk
phvlimfgpfidithpliasgklpnfpqfktqpktldelflklftpilktisphiqtvli
pstkdaisnhaaypqaslirkalqlpkrnfkcmanpssfqineiyfgcsnvdtfkdlkev
ikggttssryrldrvsehilqqrryypifpgsirtrikpkdvstkketndmeskeekvye
hisgadldvsylgltefvggfspdimiipselqhfarvvqnvvvinpgrfiratgnrgsy
aqitvqcpdledgkltlvegeepvylhnvwkrarvdlias

    Sequence, based on observed residues (ATOM records):
    >3floE (E:)
rtmrqnlqeasdvlddqiesftkiiqnhyklspndfadptiqsqseiyavgrivpdspty
dkflnpeslsletsrmggvgrrvrldlsqvnelsfflgqivafkgknangdyftvnsilp
lpypnspvstsqelqefqanlegsslkvivtcgpyfandnfslellqefidsinnevkph
vlimfgpfidithpliasgklpnfpqfktqpktldelflklftpilktisphiqtvlips
tkdaisnhaaypqaslirkalqlpkrnfkcmanpssfqineiyfgcsnvdtfkdlkevik
ggttssryrldrvsehilqqrryypifpgsirthisgadldvsylgltefvggfspdimi
ipselqhfarvvqnvvvinpgrfiratgnrgsyaqitvqcpdledgkltlvegeepvylh
nvwkrarvdlias

  • Chain 'F':
    Sequence, based on SEQRES records:
    >3floF (F:)
nlqplettitdverfkdtvtlelscpscdkrfpfggivssnyyrvsynglqckhceqlft
plqltsqiehsirahislyyagwlqcddstcgivtrqvsvfgkrclndgctgvmrykysd
kqlynqllyfdslfdceknkkqelkpiylpddldypkeqltessikalteqnrelmetgr
svvqkylndcgrryvdmtsifdfmln

    Sequence, based on observed residues (ATOM records):
    >3floF (F:)
dverfkdtvtlelscpscdkrfpfggivssnyyrvsynglqckhceqlftplqltsqieh
sirahislyyagwlqcddstcgivtrqvsvfgkrclndgctgvmrykysdkqlynqllyf
dslfdceknkkqelkpiylpddldypkeqltessikalteqnrelmetgrsvvqkylndc

  • Chain 'G':
    Sequence, based on SEQRES records:
    >3floG (G:)
kfrtmrqnlqeasdvlddqiesftkiiqnhyklspndfadptiqsqseiyavgrivpdsp
tydkflnpeslsletsrmggvgrrvrldlsqvnelsfflgqivafkgknangdyftvnsi
lplpypnspvstsqelqefqanlegsslkvivtcgpyfandnfslellqefidsinnevk
phvlimfgpfidithpliasgklpnfpqfktqpktldelflklftpilktisphiqtvli
pstkdaisnhaaypqaslirkalqlpkrnfkcmanpssfqineiyfgcsnvdtfkdlkev
ikggttssryrldrvsehilqqrryypifpgsirtrikpkdvstkketndmeskeekvye
hisgadldvsylgltefvggfspdimiipselqhfarvvqnvvvinpgrfiratgnrgsy
aqitvqcpdledgkltlvegeepvylhnvwkrarvdlias

    Sequence, based on observed residues (ATOM records):
    >3floG (G:)
rtmrqnlqeasdvlddqiesftkiiqnhyklspndfadptiqsqseiyavgrivpdspty
dkflnpeslsletsrmggvgrrvrldlsqvnelsfflgqivafkgknangdyftvnsilp
lpypnspvstsqelqefqanlegsslkvivtcgpyfandnfslellqefidsinnevkph
vlimfgpfidithpliasgklpnfpqfktqpktldelflklftpilktisphiqtvlips
tkdaisnhaaypqaslirkalqlpkrnfkcmanpssfqineiyfgcsnvdtfkdlkevik
ggttssryrldrvsehilqqrryypifpgsirthisgadldvsylgltefvggfspdimi
ipselqhfarvvqnvvvinpgrfiratgnrgsyaqitvqcpdledgkltlvegeepvylh
nvwkrarvdlias

  • Chain 'H':
    Sequence, based on SEQRES records:
    >3floH (H:)
nlqplettitdverfkdtvtlelscpscdkrfpfggivssnyyrvsynglqckhceqlft
plqltsqiehsirahislyyagwlqcddstcgivtrqvsvfgkrclndgctgvmrykysd
kqlynqllyfdslfdceknkkqelkpiylpddldypkeqltessikalteqnrelmetgr
svvqkylndcgrryvdmtsifdfmln

    Sequence, based on observed residues (ATOM records):
    >3floH (H:)
dverfkdtvtlelscpscdkrfpfggivssnyyrvsynglqckhceqlftplqltsqieh
sirahislyyagwlqcddstcgivtrqvsvfgkrclndgctgvmrykysdkqlynqllyf
dslfdceknkkqelkpiylpddldypkeqltessikalteqnrelmetgrsvvqkylndc

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >3floI (I:)
xxx

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records:
    >3floJ (J:)
xxx

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records:
    >3floK (K:)
xxx

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >3floL (L:)
xxx