PDB entry 3fjn

View 3fjn on RCSB PDB site
Description: The crystal structure of 17-alpha hydroxysteroid dehydrogenase Y224D mutant.
Class: oxidoreductase
Keywords: Aldo-keto reductase, 17-alpha-hydroxysteroid dehydrogenase, Cytoplasm, Lipid metabolism, NADP, Oxidoreductase, Phosphoprotein, Steroid metabolism
Deposited on 2008-12-14, released 2009-11-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-02-16, with a file datestamp of 2010-02-12.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.179
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1 member C21
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fjna_
  • Chain 'B':
    Compound: Aldo-keto reductase family 1 member C21
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91WR5 (Start-322)
      • engineered (223)
    Domains in SCOPe 2.08: d3fjnb_
  • Heterogens: ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fjnA (A:)
mnskchcvilndgnfipvlgfgtalplecpkskakeltkiaidagfhhfdsasvyntedh
vgeairskiadgtvrredifytskvwctslhpelvraslerslqklqfdyvdlylihypm
alkpgeenfpvdehgklifdrvdlcatweamekckdagltksigvsnfnyrqlemilnkp
glkykpvcnqvechpylnqmklldfckskdivlvaygvlgtqrdggwvdqnspvlldepv
lgsmakkynrtpalialryqlqrgivvlntslkeerikenmqvfefqlssedmkvldgln
rnmryipaaifkghpnwpfldey

    Sequence, based on observed residues (ATOM records): (download) 
    >3fjnA (A:)
skchcvilndgnfipvlgfgtalplecpkskakeltkiaidagfhhfdsasvyntedhvg
eairskiadgtvrredifytskvwctslhpelvraslerslqklqfdyvdlylihypmal
kpgeenfpvdehgklifdrvdlcatweamekckdagltksigvsnfnyrqlemilnkpgl
kykpvcnqvechpylnqmklldfckskdivlvaygvlgwvdqnspvlldepvlgsmakky
nrtpalialryqlqrgivvlntslkeerikenmqvfefqlssedmkvldglnrnmryipa
aifkghpnwpfldey

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3fjnB (B:)
mnskchcvilndgnfipvlgfgtalplecpkskakeltkiaidagfhhfdsasvyntedh
vgeairskiadgtvrredifytskvwctslhpelvraslerslqklqfdyvdlylihypm
alkpgeenfpvdehgklifdrvdlcatweamekckdagltksigvsnfnyrqlemilnkp
glkykpvcnqvechpylnqmklldfckskdivlvaygvlgtqrdggwvdqnspvlldepv
lgsmakkynrtpalialryqlqrgivvlntslkeerikenmqvfefqlssedmkvldgln
rnmryipaaifkghpnwpfldey

    Sequence, based on observed residues (ATOM records): (download) 
    >3fjnB (B:)
skchcvilndgnfipvlgfgtalplecpkskakeltkiaidagfhhfdsasvyntedhvg
eairskiadgtvrredifytskvwctslhpelvraslerslqklqfdyvdlylihypmal
kpgeenfpvdehgklifdrvdlcatweamekckdagltksigvsnfnyrqlemilnkpgl
kykpvcnqvechpylnqmklldfckskdivlvaygvlgtqrdggwvdqnspvlldepvlg
smakkynrtpalialryqlqrgivvlntslkeerikenmqvfefqlssedmkvldglnrn
mryipaaifkghpnwpfldey