PDB entry 3fji
View 3fji on RCSB PDB site
Description: Crystal structure of K12V/C83I/C117V mutant of Human acidic fibroblast growth factor
Class: hormone
Keywords: beta-trefoil, Acetylation, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, HORMONE
Deposited on
2008-12-14, released
2009-10-06
The last revision prior to the SCOPe 2.07 freeze date was dated
2009-10-20, with a file datestamp of
2009-10-16.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.212
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (17)
- engineered (88)
- engineered (122)
Domains in SCOPe 2.07: d3fjia1, d3fjia2 - Chain 'B':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (17)
- engineered (88)
- engineered (122)
Domains in SCOPe 2.07: d3fjib1, d3fjib2 - Chain 'C':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (17)
- engineered (88)
- engineered (122)
Domains in SCOPe 2.07: d3fjic1, d3fjic2 - Chain 'D':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (17)
- engineered (88)
- engineered (122)
Domains in SCOPe 2.07: d3fjid1, d3fjid2 - Heterogens: SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3fjiA (A:)
hhhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkn
gsvkrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3fjiA (A:)
hhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyik
stetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkngsv
krgprthygqkailflplpv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3fjiB (B:)
hhhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkn
gsvkrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3fjiB (B:)
hhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevy
ikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkng
svkrgprthygqkailflplpv
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3fjiC (C:)
hhhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkn
gsvkrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3fjiC (C:)
hhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevy
ikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkng
svkrgprthygqkailflplpv
- Chain 'D':
Sequence, based on SEQRES records: (download)
>3fjiD (D:)
hhhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkn
gsvkrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3fjiD (D:)
hhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyiks
tetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkngsvk
rgprthygqkailflplpv