PDB entry 3fji

View 3fji on RCSB PDB site
Description: Crystal structure of K12V/C83I/C117V mutant of Human acidic fibroblast growth factor
Class: hormone
Keywords: beta-trefoil, Acetylation, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, HORMONE
Deposited on 2008-12-14, released 2009-10-06
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-10-20, with a file datestamp of 2009-10-16.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.212
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: heparin-binding growth factor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FGF1, FGFA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered (17)
      • engineered (88)
      • engineered (122)
    Domains in SCOPe 2.04: d3fjia_
  • Chain 'B':
    Compound: heparin-binding growth factor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FGF1, FGFA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered (17)
      • engineered (88)
      • engineered (122)
    Domains in SCOPe 2.04: d3fjib_
  • Chain 'C':
    Compound: heparin-binding growth factor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FGF1, FGFA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered (17)
      • engineered (88)
      • engineered (122)
    Domains in SCOPe 2.04: d3fjic_
  • Chain 'D':
    Compound: heparin-binding growth factor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: FGF1, FGFA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered (17)
      • engineered (88)
      • engineered (122)
    Domains in SCOPe 2.04: d3fjid_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3fjiA (A:)
    hhhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
    yikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkn
    gsvkrgprthygqkailflplpvssd
    

    Sequence, based on observed residues (ATOM records): (download)
    >3fjiA (A:)
    hhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyik
    stetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkngsv
    krgprthygqkailflplpv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3fjiB (B:)
    hhhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
    yikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkn
    gsvkrgprthygqkailflplpvssd
    

    Sequence, based on observed residues (ATOM records): (download)
    >3fjiB (B:)
    hhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevy
    ikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkng
    svkrgprthygqkailflplpv
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3fjiC (C:)
    hhhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
    yikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkn
    gsvkrgprthygqkailflplpvssd
    

    Sequence, based on observed residues (ATOM records): (download)
    >3fjiC (C:)
    hhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevy
    ikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkng
    svkrgprthygqkailflplpv
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3fjiD (D:)
    hhhhhhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
    yikstetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkn
    gsvkrgprthygqkailflplpvssd
    

    Sequence, based on observed residues (ATOM records): (download)
    >3fjiD (D:)
    hhfnlppgnykkpvllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyiks
    tetgqylamdtdgllygsqtpneeilflerleenhyntyiskkhaeknwfvglkkngsvk
    rgprthygqkailflplpv