PDB entry 3fjd
View 3fjd on RCSB PDB site
Description: Crystal structure of L44F/F132W mutant of Human acidic fibroblast growth factor
Class: hormone
Keywords: beta-trefoil, Acetylation, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, HORMONE
Deposited on
2008-12-14, released
2009-10-06
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-10-13, with a file datestamp of
2009-10-09.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.19
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (49)
- engineered (137)
Domains in SCOPe 2.06: d3fjda1, d3fjda2 - Chain 'B':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (49)
- engineered (137)
Domains in SCOPe 2.06: d3fjdb1, d3fjdb2 - Heterogens: SO4, FMT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3fjdA (A:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailwlplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3fjdA (A:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailwlplpv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3fjdB (B:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailwlplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3fjdB (B:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailwlplpv