PDB entry 3fja
View 3fja on RCSB PDB site
Description: Crystal structure of F132W mutant of Human acidic fibroblast growth factor
Class: hormone
Keywords: beta-trefoil, Acetylation, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, HORMONE
Deposited on
2008-12-14, released
2009-10-06
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-10-13, with a file datestamp of
2009-10-09.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.19
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3fjaa1, d3fjaa2 - Chain 'B':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3fjab1, d3fjab2 - Heterogens: FMT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3fjaA (A:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailwlplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3fjaA (A:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailwlplpv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3fjaB (B:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailwlplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3fjaB (B:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailwlplpv