PDB entry 3fhe

View 3fhe on RCSB PDB site
Description: Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine.
Class: hydrolase/hydrolase inhibitor
Keywords: LTA4H, Leukotriene A4, Leukotriene B4 Biosynthesis, Peptidase, Hydrolase-hydrolase inhibitor complex, Structure Based Drug Design, Leukotriene biosynthesis, Metal-binding, Metalloprotease, Multifunctional enzyme, Protease
Deposited on 2008-12-09, released 2010-01-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fhea1, d3fhea2, d3fhea3
  • Heterogens: ZN, YB, ACT, IMD, 28P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fheA (A:)
mpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdl
tiekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwlt
peqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetp
dpedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetes
mlkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheish
swtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfget
hpftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksi
ttddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitak
eddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwl
rlciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvt
amlvgkdlkvd

    Sequence, based on observed residues (ATOM records): (download) 
    >3fheA (A:)
vdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdltiek
vvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltpeqt
sgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpdped
psrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesmlki
aedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishswtg
nlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgethpft
klvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksittdd
wkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitakeddl
nsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlrlci
qskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvtamlv
gkdlkvd